CAJ | 학술논문

糖尿病是严重威胁人类健康的常见病和多发病.糖尿病主要是由于胰岛β细胞选择性破坏或胰岛e细胞分泌胰岛素迟缓和胰岛素抵抗而使胰岛素相对不足所致.β细胞的数量只有减少50%～60%时才会出现相关的症状.由于胰腺位置较深,β细胞含量少,目前临床诊断主要采用有创性方法,且难于进行早期诊断.因此,通过无创性的方法进行β细胞相关代谢疾病的早期诊断,越来越受到人们的关注,影像学诊断也就成了关注焦点,但是如何进行β细胞数量和功能的评估仍是目前影像学诊断面临的重要课题.
당뇨병시엄중위협인류건강적상견병화다발병.당뇨병주요시유우이도β세포선택성파배혹이도e세포분비이도소지완화이도소저항이사이도소상대불족소치.β세포적수량지유감소50%～60%시재회출현상관적증상.유우이선위치교심,β세포함량소,목전림상진단주요채용유창성방법,차난우진행조기진단.인차,통과무창성적방법진행β세포상관대사질병적조기진단,월래월수도인문적관주,영상학진단야취성료관주초점,단시여하진행β세포수량화공능적평고잉시목전영상학진단면림적중요과제.
Diabetes mellitus is a common and frequently occurring disease which seriously threaten the health of human beings. Type 1 and type 2 diabetes respectively results from being destroyed and insufficient beta-cell mass. The associated symptoms appear until 50%-60% decrease of beta-cell mass. Because pancreas is deeply located in the body, with few beta-cell mass, the current methods of clinical diagnosis are invasive and late. So diagnosis of metabolism disease of beta-cell early and non-invasively becomes more and more popular, imaging diagnosis of diabetes mellitus becomes the focus of researches, but how to estimate the mass of beta-cell is still an important subject in imaging technology.