生物技术
生物技術
생물기술
BIOTECHNOLOGY
2010年
2期
92-95
,共4页
真菌%鞘脂%代谢%抗真菌药物
真菌%鞘脂%代謝%抗真菌藥物
진균%초지%대사%항진균약물
fungi%sphingolipid%metabolism%antifungal drug
鞘脂是真核细胞中普遍存在的成分,它在真核细胞的胞吞、胞饮、信号转导、细胞的生长、凋亡、分化、衰老等过程中起着非常重要的作用.该文论述了真菌鞘脂代谢的途径及参与其合成的相关酶和基因,并比较了真菌与哺乳动物鞘脂代谢途径的不同,旨在为研究新型无公害抗真菌药物提供理论依据.
鞘脂是真覈細胞中普遍存在的成分,它在真覈細胞的胞吞、胞飲、信號轉導、細胞的生長、凋亡、分化、衰老等過程中起著非常重要的作用.該文論述瞭真菌鞘脂代謝的途徑及參與其閤成的相關酶和基因,併比較瞭真菌與哺乳動物鞘脂代謝途徑的不同,旨在為研究新型無公害抗真菌藥物提供理論依據.
초지시진핵세포중보편존재적성분,타재진핵세포적포탄、포음、신호전도、세포적생장、조망、분화、쇠로등과정중기착비상중요적작용.해문논술료진균초지대사적도경급삼여기합성적상관매화기인,병비교료진균여포유동물초지대사도경적불동,지재위연구신형무공해항진균약물제공이론의거.
Sphingolipid is ubiquitous of components of eukaryotic cell membranes, where it play important roles in intraeelhilar endocyto-sis, endocytose, signaling transduction and in cell growth, apoptosis, differentiation, senescence, etc.The metabolism of fungi sphingo-lipid in the way of its synthesis was discussed in this article, included the relevant enzymes and genes, and compared the difference be-tween fungi and mammals in the metabolism of sphingolipid, which provides theory for designding the new antifungal gents.
