CAJ | 학술논문

肺癌肿瘤抑制因子1(TSLC1)介导细胞间相互黏附、胞内信号传导及免疫调节,在抑制肿瘤细胞侵袭和转移方面发挥着重要作用.TSLC1作为分子诊断标记物和药物治疗靶点,具有极大的应用潜力,探索其在肿瘤发生发展中的作用及其机制已成为当今的研究热点之一.
폐암종류억제인자1(TSLC1)개도세포간상호점부、포내신호전도급면역조절,재억제종류세포침습화전이방면발휘착중요작용.TSLC1작위분자진단표기물화약물치료파점,구유겁대적응용잠력,탐색기재종류발생발전중적작용급기궤제이성위당금적연구열점지일.
Tumor suppressor of lung cancer 1 (TSLC1) mediates cell-cell and cell-extracellar matrix adhesion, cellular signal transduction and immunoregulation, and additionally plays a vital role in inhibiting proliferation, migration and metastasis of tumor cells. As a novel tumor suppressor gene, TSLC1 may be regarded as a potential molecular marker for diagnosis and a pharmaceutical target. Consequently, to explore the functions and mechanism of TSLC1 in initiation and development of carcinomas has become one of the popular researches currently.