CAJ | 학술논문

目的初步探讨尼龙圈结扎胃及结肠壁全层的安全性,为不断扩展的临床应用提供依据.方法成年狗4只,在纤维胃镜及开腹直视配合下应用尼龙圈结扎胃及结肠壁全层,术后3、7、10、17 d分别行剖腹术观察结扎部位组织愈合情况.结果所有动物术后恢复良好,观察期间无感染及出血征象.剖腹检查未发现胃结肠穿孔,无局部脓肿形成.结扎部位可见溃疡样缺损.组织学检查可见胃结肠壁肌层断裂,肉芽组织连接胃结肠缺损部位,并逐渐转化为瘢痕组织.术后17 d可见再生黏膜完全覆盖缺损表面.结论尼龙圈结扎胃结肠壁全层具有一定安全性,可进一步拓宽尼龙圈结扎在临床中的应用.
목적 초보탐토니룡권결찰위급결장벽전층적안전성,위불단확전적림상응용제공의거.방법 성년구4지,재섬유위경급개복직시배합하응용니룡권결찰위급결장벽전층,술후3、7、10、17 d분별행부복술관찰결찰부위조직유합정황.결과 소유동물술후회복량호,관찰기간무감염급출혈정상.부복검사미발현위결장천공,무국부농종형성.결찰부위가견궤양양결손.조직학검사가견위결장벽기층단렬,육아조직련접위결장결손부위,병축점전화위반흔조직.술후17 d가견재생점막완전복개결손표면.결론 니룡권결찰위결장벽전층구유일정안전성,가진일보탁관니룡권결찰재림상중적응용.
Objective To evaluate the safety of endoscopic ligation of gastric and colic full-thickness wall with nylon loops.Methods Endoscopic ligation of full gastric and colic wall with detachable nylon loops, assisted by laparotomy, were performed in 4 dogs.Ligation healing was assessed on 3, 7, 10and 17 days after the procedure.Results All animals recovered after the procedure, without any clinical signs of infection or hemorrhage.Postoperative examination did not reveal gastric or colonic perforation, or local abscess.Loop ligature showed ulcer-like lesion.Histopathology revealed muscularis propria disruption, granulation tissue bridging the site of ligation and formation of scar tissue.Regenerative mucosa coyered the surface of the ligature completely 17 days after the operation.Conclusion Endoscopic ligation of gastric and colic full-thickness wall with detachable nylon loops is safe.Its application can be extended to other fields.