分析科学学报
分析科學學報
분석과학학보
JOURNAL OF ANALYTICAL SCIENCE
2000年
6期
488-489
,共2页
庞志功%汪宝琪%厉英倩
龐誌功%汪寶琪%厲英倩
방지공%왕보기%려영천
胶束荧光%丹参酮Ⅱ A%血药浓度
膠束熒光%丹參酮Ⅱ A%血藥濃度
효속형광%단삼동Ⅱ A%혈약농도
Micella fluorometry%Tanshinone Ⅱ A%Blood-drug concentration
以十二烷基磺酸钠(SLS)为胶束试剂，在优化的实验条件下，对兔体血浆中丹参酮Ⅱ A的血药浓度进行了24 h的连续监测，检出限为1.2 ×10－9 g/mL，血中丹参酮Ⅱ A的含量在2.81×10－6 ～0.30×10－6 g/mL之间。该法简便、灵敏、效果良好。
以十二烷基磺痠鈉(SLS)為膠束試劑，在優化的實驗條件下，對兔體血漿中丹參酮Ⅱ A的血藥濃度進行瞭24 h的連續鑑測，檢齣限為1.2 ×10－9 g/mL，血中丹參酮Ⅱ A的含量在2.81×10－6 ～0.30×10－6 g/mL之間。該法簡便、靈敏、效果良好。
이십이완기광산납(SLS)위효속시제，재우화적실험조건하，대토체혈장중단삼동Ⅱ A적혈약농도진행료24 h적련속감측，검출한위1.2 ×10－9 g/mL，혈중단삼동Ⅱ A적함량재2.81×10－6 ～0.30×10－6 g/mL지간。해법간편、령민、효과량호。
Using SLS as a micella reagent, the blood-drug concen tration of tanshione Ⅱ A in rabbit blood was monitored contin ously for 24 h under the optimized conditions. The detection limit was 1.2×10 -9 g/mL. The results showed that there was 2.81×10-6～0.30×10-6 g/mL of tanshinone Ⅱ A in blood. The proposed method was sim ple and sensitive with good results.
