CAJ | 학술논문

目的了解济南市碘缺乏病防治情况,评价济南市人群碘营养状况,探索适宜水碘范围,为科学调整干预策略提供依据.方法根据《全国碘缺乏病监测方案(试行)》,调查分析2003-2010年济南市碘缺乏地区居民合格碘盐食用率、居民饮用水含碘量,以及育龄妇女尿碘水平.采用直接滴定法检测盐碘、砷铈氧化还原法检测水碘,砷铈催化分光光度法测定尿碘.结果 2003 - 2010年济南市居民合格碘盐食用率均达到了90％以上.济南市10个县(市、区)水碘中位数为13.65μg/L,其中＜100μg/L的占79.82％ (4560/5713)；＞150μg/L的占12.7 3％( 727/5713).随水碘的升高(0～＜10、10 ～＜ 50、50～＜100、100 ～＜ 150、150～＜300、≥300μg/L),育龄妇女尿碘水平依次升高(中位数分别为156.56、175.81、267.04、349.00、524.22、583.20 μg/L,x2=121.20,P＜0.05),而尿碘＜100 μg/L的比例明显降低；100～ 300μg/L的比例也逐渐降低；＞300μg/L的比例则逐渐增加.结论济南市碘缺乏地区达到了消除碘缺乏病的标准,应坚持因地制宜、分类指导、科学补碘的碘缺乏病防治措施.
목적 료해제남시전결핍병방치정황,평개제남시인군전영양상황,탐색괄의수전범위,위과학조정간예책략제공의거.방법 근거《전국전결핍병감측방안(시행)》,조사분석2003-2010년제남시전결핍지구거민합격전염식용솔、거민음용수함전량,이급육령부녀뇨전수평.채용직접적정법검측염전、신시양화환원법검측수전,신시최화분광광도법측정뇨전.결과 2003 - 2010년제남시거민합격전염식용솔균체도료90％이상.제남시10개현(시、구)수전중위수위13.65μg/L,기중＜100μg/L적점79.82％ (4560/5713)；＞150μg/L적점12.7 3％( 727/5713).수수전적승고(0～＜10、10 ～＜ 50、50～＜100、100 ～＜ 150、150～＜300、≥300μg/L),육령부녀뇨전수평의차승고(중위수분별위156.56、175.81、267.04、349.00、524.22、583.20 μg/L,x2=121.20,P＜0.05),이뇨전＜100 μg/L적비례명현강저；100～ 300μg/L적비례야축점강저；＞300μg/L적비례칙축점증가.결론 제남시전결핍지구체도료소제전결핍병적표준,응견지인지제의、분류지도、과학보전적전결핍병방치조시.
Objective To find out the status of prevention and control of iodine deficiency disorders and evaluate the iodine nutritional status of Jinan residents,to explore appropriate iodine level in drinking water,and to provide a scientific basis for adjustment of intervention strategies.Methods According to the "Monitoring Program of the National Iodine Deficiency Disorders (Trial)",qualified iodized salt consumption rate,drinking water iodine content and urinary iodine levels of women of childbearing age were determined in iodine deficiency areas from 2003 to 2010.Salt iodine was detected by direct titrimetry,urinary iodine by As-Ce catalytic spectrophotometric assay and iodine in drinking water by cerous sulfate catalytic spectrophotometric method.Results Intake rate of qualified iodized salt was up to 90％ and above from 2003 to 2010,median water iodine was 13.65 μg/L in the 10 counties(cities,districts),of which less than 100 μg/L accounted for 79.82％(4560/5713 ) and ＞ 150 μg/L accounted for 12.73％(727/5713).With the increase of water iodine(0 ～＜ 10,10 ～＜ 50,50 ～＜ 100,100 ～＜ 150,150 ～＜ 300 and ≥300 μg/L),urinary iodine levels of women of childbearing age increased successively(median 156.56,175.81,267.04,349.00,524.22,583.20 μg/L,respectively,x2 =121.20,P ＜ 0.05),while the ratio of urinary iodine ＜ 100 μg/L was significantly lower.The ratio of urinary iodine between 100 and 300 μg/L was decreased gradually,but the ratio of great than 300 μg/L was gradually increased.Conclusions Iodine deficiency areas in Jinan have reached the standard of elimination of iodine deficiency disorders.We should insist to carry out our measures to suit local conditions,classified guidances and scientific principals of iodine supplementation.