中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2008年
2期
141-142
,共2页
南佳彦%朱本章%高烨%韩燕%张启云
南佳彥%硃本章%高燁%韓燕%張啟雲
남가언%주본장%고엽%한연%장계운
胰岛素%抗炎作用%NF-κB%细胞间黏附分子1
胰島素%抗炎作用%NF-κB%細胞間黏附分子1
이도소%항염작용%NF-κB%세포간점부분자1
Insulin%Anti-inflammatory effects%NF-κB%Intercellular adhesion molecule-1
将62例危重患者随机分为两组,在基础治疗相同的情况下分别给予强化胰岛素血糖控制治疗和常规治疗.观察临床疗效并测定外周血单个核细胞NF-κB活性和血浆细胞间黏附分子1(ICAM-1)水平.结果 提示强化胰岛素治疗可改善危重症患者预后,胰岛素有可靠的抗炎作用.
將62例危重患者隨機分為兩組,在基礎治療相同的情況下分彆給予彊化胰島素血糖控製治療和常規治療.觀察臨床療效併測定外週血單箇覈細胞NF-κB活性和血漿細胞間黏附分子1(ICAM-1)水平.結果 提示彊化胰島素治療可改善危重癥患者預後,胰島素有可靠的抗炎作用.
장62례위중환자수궤분위량조,재기출치료상동적정황하분별급여강화이도소혈당공제치료화상규치료.관찰림상료효병측정외주혈단개핵세포NF-κB활성화혈장세포간점부분자1(ICAM-1)수평.결과 제시강화이도소치료가개선위중증환자예후,이도소유가고적항염작용.
A total of 62 critically ill patients were randomly allocated to the intensive insulin therapy group and the conventional insulin therapy group. The effect of therapy on the prognosis, the activity of NF-κB in peripheral blood monouclear cells and plasma intercellular adhesion molecule-1 level were investigated. The results showed that the intensive insulin therapy may improve the prognosis and insulin had a reliable anti-inflammatory effect in the critically ill patients.
