国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2010年
9期
711-715
,共5页
周细胞%血脑屏障%新生血管化,生理性%内皮细胞
週細胞%血腦屏障%新生血管化,生理性%內皮細胞
주세포%혈뇌병장%신생혈관화,생이성%내피세포
Pericytes%Blood-brain barrier%Neovascularization,physiologic%Endothelial cells
周细胞是血脑屏障的一种重要细胞成分,在脑微血管生成、内皮细胞紧密连接形成、血脑屏障分化、微血管动态运动和结构稳定性方面起调节作用.周细胞在一些疾病,如脑血管病、神经退行性疾病、神经免疫性疾病和外伤性脑损伤中,呈现很独特的功能特性.文章对周细胞在血脑屏障中的作用做了综述.
週細胞是血腦屏障的一種重要細胞成分,在腦微血管生成、內皮細胞緊密連接形成、血腦屏障分化、微血管動態運動和結構穩定性方麵起調節作用.週細胞在一些疾病,如腦血管病、神經退行性疾病、神經免疫性疾病和外傷性腦損傷中,呈現很獨特的功能特性.文章對週細胞在血腦屏障中的作用做瞭綜述.
주세포시혈뇌병장적일충중요세포성분,재뇌미혈관생성、내피세포긴밀련접형성、혈뇌병장분화、미혈관동태운동화결구은정성방면기조절작용.주세포재일사질병,여뇌혈관병、신경퇴행성질병、신경면역성질병화외상성뇌손상중,정현흔독특적공능특성.문장대주세포재혈뇌병장중적작용주료종술.
Pericytes are a very important cellular constituent of the blood-brain barrier.They play a regulatory role in brain angiogenesis,endothelial cell tight junction formation,blood-brain barrier differentiation,microvascular dynamic motion and structural stability.Pericytes exhibit unique functional characteristics in some diseases,such as cerebrovascular disease,neurodegenerative disease,neuroimmune disease and traumatic brain injury.This article reviews the roles of pericytes in the blood-brain barrier.