中华神经科杂志
中華神經科雜誌
중화신경과잡지
Chinese Journal of Neurology
2009年
1期
46-49
,共4页
唐澍%赵桂萍%赵玉宾%孙相如
唐澍%趙桂萍%趙玉賓%孫相如
당주%조계평%조옥빈%손상여
眼球运动%帕金森病%眼震电图描记术
眼毬運動%帕金森病%眼震電圖描記術
안구운동%파금삼병%안진전도묘기술
Eye movements%Parkinson disease%Electronystagmography
目的 定量分析帕金森病(PD)患者眼球跟踪运动的特点,为评价PD患者的前庭功能提供依据.方法 选取30名健康人(对照组)和55例PD患者(PD组)作为受试者,PD组包括静止件震颤起病者31例(静止性震颤组),运动减少起病者23例(运动减少组),混合起病1例.对全部受试者进行眼震电图检杳.比较PD组和对照组跟踪运动增益值(gain,G)的差异,运动减少组和静止性震颤组跟踪运动的差异,PD患者双侧跟踪运动的非对称性和健康对照者的差异.结果 PD患者双侧跟踪运动的增益值(G左:0.79±0.10、G右:0.78±0.11)较对照组(G左:0.86±0.05、G右:0.85±0.06)明显降低(U=394.500、t=3.547,均P<0.01),运动减少组(G左:0.79±0.14、G右:0.75±0.14)与静止性震颤组(G左:0.79±0.06、G右:0.81±0.07)眼球跟踪运动增益值差异无统计学意义(t=-0.100、2.005,均P0.05).病例组左右两侧的跟踪运动非对称性(1.03±0.97)明显大于对照组(0.87±0.86,U=755.500,P<0.05).结论 PD患者眼球跟踪运动速度明显减慢,但不存在类型间的差异,两侧跟踪运动存在不对称性.
目的 定量分析帕金森病(PD)患者眼毬跟蹤運動的特點,為評價PD患者的前庭功能提供依據.方法 選取30名健康人(對照組)和55例PD患者(PD組)作為受試者,PD組包括靜止件震顫起病者31例(靜止性震顫組),運動減少起病者23例(運動減少組),混閤起病1例.對全部受試者進行眼震電圖檢杳.比較PD組和對照組跟蹤運動增益值(gain,G)的差異,運動減少組和靜止性震顫組跟蹤運動的差異,PD患者雙側跟蹤運動的非對稱性和健康對照者的差異.結果 PD患者雙側跟蹤運動的增益值(G左:0.79±0.10、G右:0.78±0.11)較對照組(G左:0.86±0.05、G右:0.85±0.06)明顯降低(U=394.500、t=3.547,均P<0.01),運動減少組(G左:0.79±0.14、G右:0.75±0.14)與靜止性震顫組(G左:0.79±0.06、G右:0.81±0.07)眼毬跟蹤運動增益值差異無統計學意義(t=-0.100、2.005,均P0.05).病例組左右兩側的跟蹤運動非對稱性(1.03±0.97)明顯大于對照組(0.87±0.86,U=755.500,P<0.05).結論 PD患者眼毬跟蹤運動速度明顯減慢,但不存在類型間的差異,兩側跟蹤運動存在不對稱性.
목적 정량분석파금삼병(PD)환자안구근종운동적특점,위평개PD환자적전정공능제공의거.방법 선취30명건강인(대조조)화55례PD환자(PD조)작위수시자,PD조포괄정지건진전기병자31례(정지성진전조),운동감소기병자23례(운동감소조),혼합기병1례.대전부수시자진행안진전도검묘.비교PD조화대조조근종운동증익치(gain,G)적차이,운동감소조화정지성진전조근종운동적차이,PD환자쌍측근종운동적비대칭성화건강대조자적차이.결과 PD환자쌍측근종운동적증익치(G좌:0.79±0.10、G우:0.78±0.11)교대조조(G좌:0.86±0.05、G우:0.85±0.06)명현강저(U=394.500、t=3.547,균P<0.01),운동감소조(G좌:0.79±0.14、G우:0.75±0.14)여정지성진전조(G좌:0.79±0.06、G우:0.81±0.07)안구근종운동증익치차이무통계학의의(t=-0.100、2.005,균P0.05).병례조좌우량측적근종운동비대칭성(1.03±0.97)명현대우대조조(0.87±0.86,U=755.500,P<0.05).결론 PD환자안구근종운동속도명현감만,단불존재류형간적차이,량측근종운동존재불대칭성.
Objective To evaluate the eyeball movement examination on Parkinson' s disease (PD) and investigate their vestibular function.Methods Thirty healthy volunteers and 55 PD patients served as subjects.Thirty-one patients had bradykinesia, 23 patients had resting tremor at first visit and 1 had both.Electronystagmogram examinations were performed in all the subjects.The eyeball movment gain (G) of PD group was compared with controls and the difference between the bradykinesia group and resting tremor group was analyzed.Dissymmetry of the bilateral pursuit movement was investigated.Results The eyeball movement gains decreased in PD patients (Left G 0.79±0.10, Right G 0.78±0.11) significantly (U = 394.500, t = 3.547, P < 0.01) compared with controls (Left G 0.86±0.05, Right G 0.85±0.06).There was no difference (t = -0.100,2.005, P 0.05) between the bradykinesia group (Left G 0.79± 0.14,Right G 0.74±0.14) and the resting tremor group ( Left G 0.79±0.06,Right G 0.81±0.07).The dissymmetry of the bilateral movement increased significantly (U = 755.500, P < 0.05) in PD group (1.03±0.97) than in controls (0.87±0.86).Conclusion The velocity of the eyeball movement has decreased in patients with PD.There is no difference of the pursuit gain between bradykinesia group and the resting tremor group.The bilateral vestibular function is involved dissymmetrically.
