CAJ | 학술논문

目的:比较西酞普兰与米氮平治疗老年期抑郁症的疗效和不良反应.方法:将64例老年期抑郁症患者随机分成两组,疗程8周,采用汉密尔顿抑郁量表(HAMD)和副反应量表(TESS)评定疗效和不良反应.结果:西酞普兰组和米氮平组显效率分别82.35%和76.7%,两组疗效差异无显著性(P＞0.05),西酞普兰的不良反应少于米氮平.结论:西酞普兰是一种安全、有效的抗抑郁药.
목적:비교서태보란여미담평치료노년기억욱증적료효화불량반응.방법:장64례노년기억욱증환자수궤분성량조,료정8주,채용한밀이돈억욱량표(HAMD)화부반응량표(TESS)평정료효화불량반응.결과:서태보란조화미담평조현효솔분별82.35%화76.7%,량조료효차이무현저성(P＞0.05),서태보란적불량반응소우미담평.결론:서태보란시일충안전、유효적항억욱약.
Objective:To explore the efficacy and side effects of citalopram and mirtazapine in treatment of senile depression.Methods:64 senile depressive patients were randomly divided into two groups for 8 weeks.The trerapeutic response and side effects were evaluated with the HAMD and TESS.Results:The effective rates of citalopram and mirtazapine were 82.35% and 76.7% respectively there were no significant difference in efficacy between the two groups (P＞0.05),citalopram had fewer side effects than mirtazapine.Conclusion:Citalopram is a safe and effective antidepressant.