西安交通大学学报（医学版）
西安交通大學學報（醫學版）
서안교통대학학보（의학판）
JOURNAL OF XI'AN JIAOTONG UNIVERSITY(MEDICAL SCIENCES)
2009年
6期
687-688,715
,共3页
张勇%吕毅%谢占涛%万真%胡良硕%于良%刘昌%张谞丰%马锋
張勇%呂毅%謝佔濤%萬真%鬍良碩%于良%劉昌%張谞豐%馬鋒
장용%려의%사점도%만진%호량석%우량%류창%장서봉%마봉
肝移植%巨细胞病毒%诊断%治疗
肝移植%巨細胞病毒%診斷%治療
간이식%거세포병독%진단%치료
liver transplantation%cytomegalovirus%diagnosis%treatment
目的 分析肝移植术后受体巨细胞病毒(CMV)感染的诊断和治疗.方法 回顾性分析我科2000年11月至2007年12月期间进行的肝移植病例,依据易感因素、临床症状、外周血中CMV-PP65和(或)CMV-IgM及胸片明确诊断,以更昔洛韦抗病毒治疗.结果 共收集资料111例(剔除相关资料不完整者).发现CMV感染5例,CMV感染发生率为4.5%;其中2例发生CMV肺炎,CMV肺炎发生率为1.8%(占CMV感染的40%),2例均好转.活动性CMV感染3例,2例治愈,1例好转.结论 CMV-PP65检测能够对CMV感染患者做出早期诊断并且指导治疗.更昔洛韦能够有效治疗CMV感染.
目的 分析肝移植術後受體巨細胞病毒(CMV)感染的診斷和治療.方法 迴顧性分析我科2000年11月至2007年12月期間進行的肝移植病例,依據易感因素、臨床癥狀、外週血中CMV-PP65和(或)CMV-IgM及胸片明確診斷,以更昔洛韋抗病毒治療.結果 共收集資料111例(剔除相關資料不完整者).髮現CMV感染5例,CMV感染髮生率為4.5%;其中2例髮生CMV肺炎,CMV肺炎髮生率為1.8%(佔CMV感染的40%),2例均好轉.活動性CMV感染3例,2例治愈,1例好轉.結論 CMV-PP65檢測能夠對CMV感染患者做齣早期診斷併且指導治療.更昔洛韋能夠有效治療CMV感染.
목적 분석간이식술후수체거세포병독(CMV)감염적진단화치료.방법 회고성분석아과2000년11월지2007년12월기간진행적간이식병례,의거역감인소、림상증상、외주혈중CMV-PP65화(혹)CMV-IgM급흉편명학진단,이경석락위항병독치료.결과 공수집자료111례(척제상관자료불완정자).발현CMV감염5례,CMV감염발생솔위4.5%;기중2례발생CMV폐염,CMV폐염발생솔위1.8%(점CMV감염적40%),2례균호전.활동성CMV감염3례,2례치유,1례호전.결론 CMV-PP65검측능구대CMV감염환자주출조기진단병차지도치료.경석락위능구유효치료CMV감염.
Objective To study the diagnosis and treatment of cytomegalovirus (CMV) infection after liver transplantation. Methods The clinical data of 111 patients who received liver transplantation from November 2000 to December 2007 in our hospital were analyzed retrospectively. The recipients were diagnosed as having CMV infection by the predisposing factors, clinical symptoms and detection of CMV-PP65 and CMV-IgM in peripheral blood specimens in combination with chest X-ray. The treatment of CMV infection was administration of Ganciclovir. Results Five recipients were diagnosed as having CMV infection, with the incidence of 4.5%. Two were diagnosed as having CMV pneumonitis, with the incidence of 1.8% (40% of the recipients having CMV infection). Two were both improved. Three were diagnosed as having CMV active infection. Two of them were cured and one was improved. Conclusion The detection of CMV-PP65 is necessary for early diagnosis and guiding treatment of CMV infection. Ganciclovir can exert significant therapeutic effects on CMV infection.
