CAJ | 학술논문

目的探讨左心室射血分数(LVEF)≤40%的冠心病患者接受经皮冠状动脉介入治疗术(PCI)或冠状动脉旁路移植术(CABG)两种不同血运重建策略的效果.方法将196例LVEF≤40%的冠心病患者分为PCI和CABG组.回顾性比较其临床资料、血运重建情况、药物治疗效果、院内及随访不良心血管事件(MACCE),并进行生存分析.结果寿命表法示PCI组与CABG组30 d生存率(96%与94%)、1年生存率(95%与92%)、2年生存率(93%与87%)相似,并且2组COX生存曲线差异无统计学意义(P=0.249);PCI组与CABG组30 d无MACCE事件生存率(92%与92%)、1年无MACCE事件生存率(86%与88%)相似,而CABG组2年无MACCE事件生存率略高于PCI组(83%与72%),但2组COX无MACCE事件生存曲线差异无统计学意义(P=0.662).结论 LVEF≤40%患者接受PCI治疗可以取得与接受CABG治疗相似的急性期和长期生存率.
목적 탐토좌심실사혈분수(LVEF)≤40%적관심병환자접수경피관상동맥개입치료술(PCI)혹관상동맥방로이식술(CABG)량충불동혈운중건책략적효과.방법 장196례LVEF≤40%적관심병환자분위PCI화CABG조.회고성비교기림상자료、혈운중건정황、약물치료효과、원내급수방불양심혈관사건(MACCE),병진행생존분석.결과 수명표법시PCI조여CABG조30 d생존솔(96%여94%)、1년생존솔(95%여92%)、2년생존솔(93%여87%)상사,병차2조COX생존곡선차이무통계학의의(P=0.249);PCI조여CABG조30 d무MACCE사건생존솔(92%여92%)、1년무MACCE사건생존솔(86%여88%)상사,이CABG조2년무MACCE사건생존솔략고우PCI조(83%여72%),단2조COX무MACCE사건생존곡선차이무통계학의의(P=0.662).결론 LVEF≤40%환자접수PCI치료가이취득여접수CABG치료상사적급성기화장기생존솔.
Objective To investigate the effect of PCI/CABG for the patients with coronary artery disease(CAD) with LVEF≤40%. Methods 196 CAD patients with LVEF≤40% were divided into PCI (n = 106) and CABG group (n=90). The clinical factors, revaseularization, medication, and in-hospital and follow-up malignant cardiological events(MACCE) were retrospectively compared,and the survival curve were drew by COX regression.Results Survival rate of the PCI group and CABG group in 30-day (96% vs. 94% ), 1-year(95 % vs. 92% ), and 2-year(93% vs. 87% )were similar. There was no MACCE within 30 days in the two groups(92% vs. 92% ) and 1-year survival rate without MACCE was similar in the two groups(86% vs. 88% ). CABG group had higher 2- year survival rate without MACCE than PCI group (83%vs. 72% ). But the COX survival curves of the two group were not signifi-cantly different (P=0. 662). Conclusion The patients with LVEF ≤ 40% undergoing PCI have short-term and long-term survival rate similar to those accepting CABG.