天然产物研究与开发
天然產物研究與開髮
천연산물연구여개발
NATURAL PRODUCT RESEARCH AND DEVELOPMENT
2012年
4期
427-431,449
,共6页
张飞%覃江江%成向荣%金慧子%张卫东
張飛%覃江江%成嚮榮%金慧子%張衛東
장비%담강강%성향영%금혜자%장위동
旋覆花属%湖北旋覆花%单萜%生物碱
鏇覆花屬%湖北鏇覆花%單萜%生物堿
선복화속%호북선복화%단첩%생물감
Inuda%Inula hupehensis%monoterpenes%alkaloids
从湖北旋覆花(Inula hupehensis)地上部分分离得到19个化合物,经波谱数据分析分别鉴定为9-羟基-百里香酚(1),8,10-去氢-β-羟基-百里香酚(2),2-羟基-4-甲基苯乙酮(3),8,9-双羟基-9-百里香酚(4),10-羟基-8,9-双氧亚异丙基百里香酚(5),8,10-二羟基-9-异丁酰百里香酚(6),8-羟基-9-异丁酰-10-(2-甲基丁酰)百里香酚(7),8,9,10-三羟基百里香酚(8),8-羟基-9,10-二异丁酰百里香酚(9),neoechimulin A(10),3-醛基吲哚(11),3-羟乙酰基吲哚(12),丁香酸(13),4,6-二羟基-2-甲氧基苯乙酮(14),7-甲氧基-8-羟基香豆索(15),6-甲氧基山奈酚(16),(+)-正丁香酯索(17),β-棕榈精(18)和豆甾醇(19).除了化合物8和9外,其他化合物均为首次从该植物中分离得到.
從湖北鏇覆花(Inula hupehensis)地上部分分離得到19箇化閤物,經波譜數據分析分彆鑒定為9-羥基-百裏香酚(1),8,10-去氫-β-羥基-百裏香酚(2),2-羥基-4-甲基苯乙酮(3),8,9-雙羥基-9-百裏香酚(4),10-羥基-8,9-雙氧亞異丙基百裏香酚(5),8,10-二羥基-9-異丁酰百裏香酚(6),8-羥基-9-異丁酰-10-(2-甲基丁酰)百裏香酚(7),8,9,10-三羥基百裏香酚(8),8-羥基-9,10-二異丁酰百裏香酚(9),neoechimulin A(10),3-醛基吲哚(11),3-羥乙酰基吲哚(12),丁香痠(13),4,6-二羥基-2-甲氧基苯乙酮(14),7-甲氧基-8-羥基香豆索(15),6-甲氧基山奈酚(16),(+)-正丁香酯索(17),β-棕櫚精(18)和豆甾醇(19).除瞭化閤物8和9外,其他化閤物均為首次從該植物中分離得到.
종호북선복화(Inula hupehensis)지상부분분리득도19개화합물,경파보수거분석분별감정위9-간기-백리향분(1),8,10-거경-β-간기-백리향분(2),2-간기-4-갑기분을동(3),8,9-쌍간기-9-백리향분(4),10-간기-8,9-쌍양아이병기백리향분(5),8,10-이간기-9-이정선백리향분(6),8-간기-9-이정선-10-(2-갑기정선)백리향분(7),8,9,10-삼간기백리향분(8),8-간기-9,10-이이정선백리향분(9),neoechimulin A(10),3-철기신타(11),3-간을선기신타(12),정향산(13),4,6-이간기-2-갑양기분을동(14),7-갑양기-8-간기향두색(15),6-갑양기산내분(16),(+)-정정향지색(17),β-종려정(18)화두치순(19).제료화합물8화9외,기타화합물균위수차종해식물중분리득도.
Nineteen compounds were isolated from the aerial parts of Inula hupehensis.On the basis of spectral data,their structures were identified as 9-hydroxythymol ( 1 ),8,10-dehydro-9-hydroxythymol ( 2 ),2-hydroxy-4-methylacetophenone (3),8,9-dihydroxythymol (4),10-hydroxy-8,9-dioxyisopropylidenethymd ( 5 ),8,10-dihydroxy-9-isobutyryloxy-thymol (6),8-hydroxy-9- [ ( isobutyryl ) oxy ] -10- (2-methylbutanoyl) thymol ( 7 ),8,9,10-trihydroxythymol ( 8 ),8 -hydroxy-9,10-diisobutyryloxythymol ( 9 ),neoechinulin A ( 10 ),3-formyl-indole ( 11 ),3-( hydroxyl-acetyl ) -1H-indole ( 12 ),syringic acid ( 13 ),4,6-dihydroxy-2-methoxyacetophenone ( 14 ),daphnetin 7 -methyl ether (15),6-methoxykaemaferol (16),( + )-syringaresinol (17),a-monopalmitin (18),and stigmasterol (19).All the compounds except compounds 8 and 9 were isolated from this plant for the first time.