CAJ | 학술논문

目的探讨十二指肠间质瘤临床、内镜及病理特点.方法回顾性分析经手术和病理确诊的15例十二指肠间质瘤患者的临床、内镜及病理资料.结果以黑便伴贫血为主要表现12例,间断腹痛l例,腹胀1例,腹部肿物1例.病灶位于降部10例,水平段4例,球部1例.病理学资料肿瘤直径2～15 cm,平均6.1 cm.组织病理检查,梭形细胞型例,上皮样细胞型4例,混合型2例.CD117和CD34阳性表达率分别为86.6%和53.3%.病理诊断良性间质瘤5例,恶性8例,潜在恶性2例.结论十二指肠间质瘤临床及内镜下缺乏特异性表现,内镜下活检阳性率低,诊断依赖病理及免疫组化.
목적 탐토십이지장간질류림상、내경급병리특점.방법 회고성분석경수술화병리학진적15례십이지장간질류환자적림상、내경급병리자료.결과 이흑편반빈혈위주요표현12례,간단복통l례,복창1례,복부종물1례.병조위우강부10례,수평단4례,구부1례.병이학자료종류직경2～15 cm,평균6.1 cm.조직병리검사,사형세포형례,상피양세포형4례,혼합형2례.CD117화CD34양성표체솔분별위86.6%화53.3%.병리진단량성간질류5례,악성8례,잠재악성2례.결론 십이지장간질류림상급내경하결핍특이성표현,내경하활검양성솔저,진단의뢰병리급면역조화.
Objective To investigate the clinical characteristics,the endoscopic features,and patholog- ic morphology of duodenal gastrointestinal strnmal tumors(GISTs). Methods The clinical data of 15 GIST pa- tients were retrospectively analyzed. Results Common symptoms of GISTs were non-specific, included digestive tract hemorrhage and anemia(12/15) ,abdominal pain(1/15) ,abdominal masses(1/15) ,fullness(1/15). The lesions of duodenal GISTs mainly located in the descending duodenum (10/15) , in the horizontal part(4/15), and the bulb (1/15). The diameters of the masses ranged from 2 cm to 15 cm with an average of 6. 1 cm. Histio- pathologicaly,the types of tumors were classified as spindle cells tumors(9/15)and epithelioid cells tumors(4/ 15) ,and mixed cells tumors(2/15). The immunohistochemical results of GISTs showed that the positive rates of CD117 was 86. 6% , CD34 was 53.3%. 5 cases were benign. 2 cases were potentially malignant and 8 cases were malignant. Conclusion GISTs has no specific clinical and endoscopic feature. Final diagnosis should be based on pathology and immunohistochemics.