CAJ | 학술논문

目的了解天津地区10126名健康体检人群糖调节受损的检出率并分析其危险因素.方法对10126名体检者进行资料收集,按照1999年WHO糖尿病诊断标准分组,计算检出率,比较分析各组间临床特征,率的比较采用x2检验,两组间均数比较采用t检验,多组间均数比较采用方差分析,P ＜0.05为差异有统计学意义.运用多因素Logistic回归分析,探讨影响糖调节受损发生的危险因素.结果男性糖调节受损检出率明显高于女性(x2=136.2,P＜0.05)；糖代谢异常检出率随着年龄的增加而增加,差异具有统计学意义(P＜0.05)；糖调节受损各亚组的临床特征正态性检验和方差齐性检验显示,各组年龄、体质指数、腰围、收缩压、舒张压、总胆同醇、三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇以及血尿酸皆呈正态分布且方差齐,方差分析显示,不同组各临床特征均值差异有统计学意义(P＜0.05).logistic回归分析显示年龄增加、男性、有糖尿病家族史、超重/肥胖、高血压、高三酰甘油、高血尿酸是该组体检人群的糖调节受损发生的危险因素.结论应对具有超重(肥胖)、糖尿病家族史、高血压、高三酰甘油、高血尿酸的中老年人群定期进行糖尿病专项检查,尽早发现糖调节受损、及时进行生活及药物干预,以减缓糖调节受损发展为糖尿病.
목적 료해천진지구10126명건강체검인군당조절수손적검출솔병분석기위험인소.방법 대10126명체검자진행자료수집,안조1999년WHO당뇨병진단표준분조,계산검출솔,비교분석각조간림상특정,솔적비교채용x2검험,량조간균수비교채용t검험,다조간균수비교채용방차분석,P ＜0.05위차이유통계학의의.운용다인소Logistic회귀분석,탐토영향당조절수손발생적위험인소.결과 남성당조절수손검출솔명현고우녀성(x2=136.2,P＜0.05)；당대사이상검출솔수착년령적증가이증가,차이구유통계학의의(P＜0.05)；당조절수손각아조적림상특정정태성검험화방차제성검험현시,각조년령、체질지수、요위、수축압、서장압、총담동순、삼선감유、고밀도지단백담고순、저밀도지단백담고순이급혈뇨산개정정태분포차방차제,방차분석현시,불동조각림상특정균치차이유통계학의의(P＜0.05).logistic회귀분석현시년령증가、남성、유당뇨병가족사、초중/비반、고혈압、고삼선감유、고혈뇨산시해조체검인군적당조절수손발생적위험인소.결론 응대구유초중(비반)、당뇨병가족사、고혈압、고삼선감유、고혈뇨산적중노년인군정기진행당뇨병전항검사,진조발현당조절수손、급시진행생활급약물간예,이감완당조절수손발전위당뇨병.
Objective To investigate the prevalence and risk factors of impaired glucose regulation (IGF) in health check-up populations in Tianjin.Methods A total of10126 individuals were assigned to group according the1999 World Health Organization (WHO) criteria for diabetes mellitus ( DM ).Clinical characteristics and the prevalence of DM were compared between the groups. Student's t test,Chi-square test and logistic regression were used for data analysis.Results The incidence of IGR was much higher in male than in female (x3 =136.2,P ＜0.05).Abnormal glucose metabolism showed an increasing trend with age ( P＜0.05 ).In logistic regression analysis,age,male,family history of DM,overweight/obesity,hypertension,hypertriglyceridemia and hyperuricemia were risk factors of IGR.Conclusion Age,male,overweight/obesity,family history of DM,hypertension,hypertriglyceridemia and hyperuricemia could be risk factors of IGR.Early screening and intervention may help to prevent the development of DM.