中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2011年
6期
423-425
,共3页
诱发电位,视觉%屈光不正%弱视%儿童%年龄
誘髮電位,視覺%屈光不正%弱視%兒童%年齡
유발전위,시각%굴광불정%약시%인동%년령
Evoked potentials,visual%Refractive errors%Amblyopia%Children%Age
目的 分析屈光不正性弱视儿童图形视觉诱发电位(PVEP)检测结果的特点及年龄对其的影响.方法 回顾性系列病例研究.等效球镜为远视的屈光不正性弱视患儿92例(184眼),按最佳矫正视力0.8～0.6、0.5～0.2、≤0.1三个级别分为轻度弱视组108眼,中度弱视组65眼,重度弱视组11眼.每组又以6岁为界进行分组,分为＜6岁组和≥6岁组.采用视觉电生理检查系统检测PVEP,对弱视组间差异行单因素方差分析,同一程度弱视组中的不同年龄组间行独立样本t检验,比较不同弱视程度组间及不同年龄组间P100波潜伏期(LP100)及振幅(AP100)的差异.结果 随弱视程度加重,PVEP的LP100延长,三组间差异有统计学意义(F=151.30,P＜0.01),两两间差异均有统计学意义(P＜0.01).三组间AP100差异有统计学意义(F=13.59,P＜0.05),两两比较示,重度组的AP100明显较其余两组低,差异有统计学意义(P＜0.01),中度组较轻度组低,但差异无统计学意义.轻度组中,年龄≥6岁组与＜6岁组比较,LP100明显延长,AP100降低,差异有统计学意义(t=5.08、7.45,P＜0.01)；中度组也呈类似表现(t=4.68、4.27,P＜0.01)；重度组结果类似,但由于例数少,未进行统计分析.结论 PVEP的LP100、AP100可作为衡量儿童屈光不正性弱视严重程度的客观指标,同时对结果进行分析时应充分考虑年龄的影响.
目的 分析屈光不正性弱視兒童圖形視覺誘髮電位(PVEP)檢測結果的特點及年齡對其的影響.方法 迴顧性繫列病例研究.等效毬鏡為遠視的屈光不正性弱視患兒92例(184眼),按最佳矯正視力0.8～0.6、0.5～0.2、≤0.1三箇級彆分為輕度弱視組108眼,中度弱視組65眼,重度弱視組11眼.每組又以6歲為界進行分組,分為＜6歲組和≥6歲組.採用視覺電生理檢查繫統檢測PVEP,對弱視組間差異行單因素方差分析,同一程度弱視組中的不同年齡組間行獨立樣本t檢驗,比較不同弱視程度組間及不同年齡組間P100波潛伏期(LP100)及振幅(AP100)的差異.結果 隨弱視程度加重,PVEP的LP100延長,三組間差異有統計學意義(F=151.30,P＜0.01),兩兩間差異均有統計學意義(P＜0.01).三組間AP100差異有統計學意義(F=13.59,P＜0.05),兩兩比較示,重度組的AP100明顯較其餘兩組低,差異有統計學意義(P＜0.01),中度組較輕度組低,但差異無統計學意義.輕度組中,年齡≥6歲組與＜6歲組比較,LP100明顯延長,AP100降低,差異有統計學意義(t=5.08、7.45,P＜0.01)；中度組也呈類似錶現(t=4.68、4.27,P＜0.01)；重度組結果類似,但由于例數少,未進行統計分析.結論 PVEP的LP100、AP100可作為衡量兒童屈光不正性弱視嚴重程度的客觀指標,同時對結果進行分析時應充分攷慮年齡的影響.
목적 분석굴광불정성약시인동도형시각유발전위(PVEP)검측결과적특점급년령대기적영향.방법 회고성계렬병례연구.등효구경위원시적굴광불정성약시환인92례(184안),안최가교정시력0.8～0.6、0.5～0.2、≤0.1삼개급별분위경도약시조108안,중도약시조65안,중도약시조11안.매조우이6세위계진행분조,분위＜6세조화≥6세조.채용시각전생리검사계통검측PVEP,대약시조간차이행단인소방차분석,동일정도약시조중적불동년령조간행독립양본t검험,비교불동약시정도조간급불동년령조간P100파잠복기(LP100)급진폭(AP100)적차이.결과 수약시정도가중,PVEP적LP100연장,삼조간차이유통계학의의(F=151.30,P＜0.01),량량간차이균유통계학의의(P＜0.01).삼조간AP100차이유통계학의의(F=13.59,P＜0.05),량량비교시,중도조적AP100명현교기여량조저,차이유통계학의의(P＜0.01),중도조교경도조저,단차이무통계학의의.경도조중,년령≥6세조여＜6세조비교,LP100명현연장,AP100강저,차이유통계학의의(t=5.08、7.45,P＜0.01)；중도조야정유사표현(t=4.68、4.27,P＜0.01)；중도조결과유사,단유우례수소,미진행통계분석.결론 PVEP적LP100、AP100가작위형량인동굴광불정성약시엄중정도적객관지표,동시대결과진행분석시응충분고필년령적영향.
Objective To analyze the characteristics of pattern visual evoked potentials (PVEPs) and the effect of age in children with ametropic amblyopia.Methods Ninety-two children (184 eyes) with hyperopic amblyopia (spherical equivalent refractions) were analyzed retrospectively.Subjects were categorized into three groups based on the best corrected visual acuity (BCVA): mild amblyopia group (0.8-0.6),108 eyes; moderate amblyopia group (0.5-0.2),65 eyes; severe amblyopia group (BCVA≤0.1),11 eyes.Each group was further divided into two subgroups based on age: ＜6 years and ≥6 years. PVEPs were collected with a visual electrophysiological examination system. The differences between the latency (LP100) and amplitude (AP100) of the PVEP among different amblyopie groups and age subgroups were compared statistically with a one-way ANOVA and an independent samples t test.Results With an increase in the degree of amblyopia, the LP100 of the PVEP increased and the AP100 of the PVEP decreased.The differences between groups in the LP100 of the PVEP were statistically significant (F=151.30,P＜0.01).The differences between every two groups were statistically significant (P＜0.01).The differences between groups in the AP100 of the PVEP were statistically significant (F=13.59,P＜0.05).The differences between severe amblyopia and the other two groups were statistically significant (P＜0.01),but no statistically significant differences were found between the moderate and mild groups.Within the mild and moderate amblyopic groups,the LP100 of the ≥6 years of age group were longer than those of the ＜6 years of age group,and the AP100 of the former were less than those of the latter.The differences were statistically significant (mild group: t=5.08, 7.45, P＜0.01; moderate group: t=4.68, 4.27, P＜0.01).The severe group showed similar results but without statistical analysis due to fewer cases.Conclusion The LP100 and AP100 of the PVEP can be used to objectively assess the degree of ametropic amblyopia in children while the influence of age should also be considered.
