CAJ | 학술논문

因创伤、肿瘤切除及先天畸形导致的组织器官缺损,一直是困扰临床医生的棘手难题.目前临床上常用的组织器官重建与修复方法不外乎组织器官移植或生物替代物应用,这些方法虽然各有优点,但总的来说不尽人意.再生医学则是在再生生物学研究的基础上,运用以细胞移植为基础的细胞治疗学及以生物材料为支架的组织工程学原理,激发体内成体干细胞的再生,从而修复缺损或损害组织器官的结构和功能.重点综述再生医学基础研究方面的相关进展.
인창상、종류절제급선천기형도치적조직기관결손,일직시곤우림상의생적극수난제.목전림상상상용적조직기관중건여수복방법불외호조직기관이식혹생물체대물응용,저사방법수연각유우점,단총적래설불진인의.재생의학칙시재재생생물학연구적기출상,운용이세포이식위기출적세포치료학급이생물재료위지가적조직공정학원리,격발체내성체간세포적재생,종이수복결손혹손해조직기관적결구화공능.중점종술재생의학기출연구방면적상관진전.
Damage of tissues and organs by wound,tumor resection,and congenital malformation is always the tough problems to clinician.At present,the damaged tissues and organs are usually replaced by tissue and organ transplantation or by bionic implantation in clinic.Although these methods have some advantages respectively,they have some serious drawbacks at the same times.Regenerative medicine,which depends on the findings of regenerative biology research,applies the cellular therapeutics based on cell transplantation and the principle of tissue engineering with biomaterial as scaffolds to the repair or replacement of the damaged tissues or organs.The goal of the regenerative medicine is to reconstruct the structure and restore the function of damaged tissues or organs by promoting the regenerative potential of adult stem ceils(ASC)in vivo.This paper focuses on the recent research progress in the field of regenerative biology and medicine.