CAJ | 학술논문

miRNA(microRNA)是一类非编码RNA，长度通常为21 ～ 25个核苷酸。通过和靶mRNA的互补结合抑制蛋白表达，对机体进行多方面的调控。miRNA在多种疾病中的调控作用已得到证实，目前研究表明，miRNA和某些皮肤疾病存在一定的相关性，并在皮肤中的表达具有特征性，可以在不同种属、不同组织及不同疾病中发挥调节作用。进一步研究miRNA与皮肤疾病之间的关系也为疾病的治疗提供了新的思路及新的靶点。
miRNA(microRNA)시일류비편마RNA，장도통상위21 ～ 25개핵감산。통과화파mRNA적호보결합억제단백표체，대궤체진행다방면적조공。miRNA재다충질병중적조공작용이득도증실，목전연구표명，miRNA화모사피부질병존재일정적상관성，병재피부중적표체구유특정성，가이재불동충속、불동조직급불동질병중발휘조절작용。진일보연구miRNA여피부질병지간적관계야위질병적치료제공료신적사로급신적파점。
miRNAs (microRNAs)are a class of small, non-encoding, endogenous RNAs of 21-25 nucleotides (nts) in length. By binding to target mRNAs, they exert various modulatory effects in different species, tissues and diseases. Also, it has been demonstrated that they are associated with some dermatoses and characteristically expressed in these dermatoses. Further investigation into the relationship between miRNAs and skin diseases will provide new ideas and targets for the treatment of diseases.