中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
20期
2771-2772
,共2页
利托君%硫酸镁%沙丁胺醇%早产
利託君%硫痠鎂%沙丁胺醇%早產
리탁군%류산미%사정알순%조산
Ritodrine%Magnesium sulfate%Salbutamol%Premature
目的 比较三种不同配伍保胎药物治疗早产的临床疗效.方法 早产病例共150例,随机分为三组,即利托君组、硫酸镁联合沙丁胺醇组、硫酸镁组,观察各组治疗后孕妇的的宫缩抑制情况、起效时间、累计用药时间、延长孕期时间.结果 利托君组、硫酸镁联合沙丁胺醇组、硫酸镁组的成功率各为94%、78%、70%,利托君组明显优于联合组和硫酸镁组,显效时间分别为(2.16±0.91)h、(4.14±1.07)h、(5.12±1.45)h,三组间比较均有统计学意义(均P＜0.05),累计用药时间分别为(7.04±1.16)d、(7.46±1.20)d、(7.06±2.78)d,三组间比较无统计学意义(均P＜0.05);延长妊娠平均天数各为(22.08±7.32)d、(17.42±5.85)d、(11.82±5.04)d,三组间比较均有统计学意义(均P＜0.05).结论 单独使用利托君及硫酸镁联合沙丁胺醇治疗早产明显优于硫酸镁单独使用组.
目的 比較三種不同配伍保胎藥物治療早產的臨床療效.方法 早產病例共150例,隨機分為三組,即利託君組、硫痠鎂聯閤沙丁胺醇組、硫痠鎂組,觀察各組治療後孕婦的的宮縮抑製情況、起效時間、纍計用藥時間、延長孕期時間.結果 利託君組、硫痠鎂聯閤沙丁胺醇組、硫痠鎂組的成功率各為94%、78%、70%,利託君組明顯優于聯閤組和硫痠鎂組,顯效時間分彆為(2.16±0.91)h、(4.14±1.07)h、(5.12±1.45)h,三組間比較均有統計學意義(均P＜0.05),纍計用藥時間分彆為(7.04±1.16)d、(7.46±1.20)d、(7.06±2.78)d,三組間比較無統計學意義(均P＜0.05);延長妊娠平均天數各為(22.08±7.32)d、(17.42±5.85)d、(11.82±5.04)d,三組間比較均有統計學意義(均P＜0.05).結論 單獨使用利託君及硫痠鎂聯閤沙丁胺醇治療早產明顯優于硫痠鎂單獨使用組.
목적 비교삼충불동배오보태약물치료조산적림상료효.방법 조산병례공150례,수궤분위삼조,즉리탁군조、류산미연합사정알순조、류산미조,관찰각조치료후잉부적적궁축억제정황、기효시간、루계용약시간、연장잉기시간.결과 리탁군조、류산미연합사정알순조、류산미조적성공솔각위94%、78%、70%,리탁군조명현우우연합조화류산미조,현효시간분별위(2.16±0.91)h、(4.14±1.07)h、(5.12±1.45)h,삼조간비교균유통계학의의(균P＜0.05),루계용약시간분별위(7.04±1.16)d、(7.46±1.20)d、(7.06±2.78)d,삼조간비교무통계학의의(균P＜0.05);연장임신평균천수각위(22.08±7.32)d、(17.42±5.85)d、(11.82±5.04)d,삼조간비교균유통계학의의(균P＜0.05).결론 단독사용리탁군급류산미연합사정알순치료조산명현우우류산미단독사용조.
Objective To compare the clinical effect of three different methods in treatment of premature.Methods 150 premature patients were randomly divided into three groups,50 cases for each group,received treatments with ritodrine,magnesium sulfate plus salbutamol,or magnesium sulfate alone respectively. The tensity of uterine contraction, the interval between drug administrations and the relief of uterine contraction, the accumulative drug using time, the elongated pregnancy durations were observed for the dertermination of effectiveness. Results The group treated with ritodrine, magnesium sulfate plus salbutamol or magnesium sulfate were effective in 94%, 78%,70% of patients of each group, and it showed that ritodrine was more effective than the combination and magnesium sulfate. The intervals of drug using and contraction relief were statistically different among three groups, (2. 16 ±0. 91)h,(4. 14 ± 1.07)h,(5.12 ± 1.45) h for each(all P ＜0.05).The cumulative drug using times were(7. 04 ±1. 16) d, (7.46 ± 1.20) d, (7.06 ± 2.78) d for three groups and proved not to be statistically significant ( all P ＞0. 05 ). The elongated pregnancy durations were (22.08 ± 7.32 ) d, ( 17.42 ± 5.85 ) d and ( 11.82 ± 5.04 ) d, and significantly different in three groups ( all P ＜ 0. 05 ). Conclusion The treatment of premature with ritodrine or the combination of magnesium sulfate and salbutamol was superior to using magnesium sulfate alone.
