CAJ | 학술논문

目的评价疏血通在急性缺血性脑卒中的临床疗效.方法选择急性缺血性脑卒中患者196例,按随机数字表法分为治疗组(98例)和对照组(98例),分别在入院时及治疗后2周进行神经功能缺损评分、认知功能障碍评估及临床结局评定,并用经颅多普勒监测治疗前后脑血流量变化.结果治疗组神经功能及临床结局改善及明显改善率明显高于对照组,而恶化病例明显减少.2组治疗后认知功能障碍评分均较治疗前明显改善,差异有统计学意义(P＜0.05),其中治疗组改善更显著.治疗后2组脑血流量较治疗前明显增加,差异有统计学意义(P＜0.05),其中治疗组改善更显著.结论疏血通治疗急性缺血性脑卒中疗效显著,值得推广应用.
목적 평개소혈통재급성결혈성뇌졸중적림상료효.방법 선택급성결혈성뇌졸중환자196례,안수궤수자표법분위치료조(98례)화대조조(98례),분별재입원시급치료후2주진행신경공능결손평분、인지공능장애평고급림상결국평정,병용경로다보륵감측치료전후뇌혈류량변화.결과 치료조신경공능급림상결국개선급명현개선솔명현고우대조조,이악화병례명현감소.2조치료후인지공능장애평분균교치료전명현개선,차이유통계학의의(P＜0.05),기중치료조개선경현저.치료후2조뇌혈류량교치료전명현증가,차이유통계학의의(P＜0.05),기중치료조개선경현저.결론 소혈통치료급성결혈성뇌졸중료효현저,치득추엄응용.
Objective To evaluate the therapeutic effect of Shuxuetong injection on acute ischemic stroke. Methods One hundred and ninety-six patients with acute ischemic stroke were randomly divided into Shuxuetong injection treatment group (n=98) and control group (n=98). The neurological deficiency scores, scores of cognitive dysfunction and clinical outcomes were evaluated; and the cerebral blood flow were evaluated by Doppler before treatment and 2 weeks after the therapy.Results The improvement of neurological function and clinical outcomes in the Shuxuetong injection treatment group was more obvious as compared with that in the control group and the improvement rate of patients in the treatment group was higher than that in the controls; Patients in the Shuxuetong injection treatment group enjoyed less worsening than the controls. The cognitive dysfunction 2 weeks after the therapy were significantly improved as compared with those before treatment (P＜0.05); and the cerebral blood flow after the treatment was significantly increased as compared with that before the treatment (P＜0.05); these improvements in the Shuxuetong injection treatment group were much obvious as compared with those in the controls. Conclusion Shuxuetong is effective in treating cerebral ischemic patients.