中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2011年
1期
58-60
,共3页
骨质疏松/代谢%钙/代谢%磷/代谢%股骨/代谢%血清/代谢
骨質疏鬆/代謝%鈣/代謝%燐/代謝%股骨/代謝%血清/代謝
골질소송/대사%개/대사%린/대사%고골/대사%혈청/대사
Osteoporosis/ME%Calcium/ME%Phosphorus/ME%Femur/ME%Serum/ME
目的 探讨骨质疏松症的大鼠的股骨中钙、磷与血请中钙、磷含量的相关性.方法 用切除双侧卵巢制作大鼠骨质疏松症动物模型,用ICP电感耦合等离子体发射光谱法测定实验组和对照组股骨中和血清中钙、磷的含量.结果 实验组大鼠股骨中的钙、磷含量明显低于对照组钙、磷的含量[Ca:(218.59±10.43)mg/L vs(253.32±7.54)mg/L;P:(127.82±3.71)mg/L vs(142.18±5.99)mg/L,P＜0.01],而血清中的钙、磷含量明显高于对照组钙、磷的含量[Ca:(99.45±0.76)mg/L vs(97.56±0.80)mg/L;P:(67.68±1.63)mg/L vs(60.00±1.18)mg/L,P＜0.01].结论 股骨中钙、磷含量的明显减少,对应血清中钙、磷含量的增加是导致骨质疏松症的病因之一.
目的 探討骨質疏鬆癥的大鼠的股骨中鈣、燐與血請中鈣、燐含量的相關性.方法 用切除雙側卵巢製作大鼠骨質疏鬆癥動物模型,用ICP電感耦閤等離子體髮射光譜法測定實驗組和對照組股骨中和血清中鈣、燐的含量.結果 實驗組大鼠股骨中的鈣、燐含量明顯低于對照組鈣、燐的含量[Ca:(218.59±10.43)mg/L vs(253.32±7.54)mg/L;P:(127.82±3.71)mg/L vs(142.18±5.99)mg/L,P＜0.01],而血清中的鈣、燐含量明顯高于對照組鈣、燐的含量[Ca:(99.45±0.76)mg/L vs(97.56±0.80)mg/L;P:(67.68±1.63)mg/L vs(60.00±1.18)mg/L,P＜0.01].結論 股骨中鈣、燐含量的明顯減少,對應血清中鈣、燐含量的增加是導緻骨質疏鬆癥的病因之一.
목적 탐토골질소송증적대서적고골중개、린여혈청중개、린함량적상관성.방법 용절제쌍측란소제작대서골질소송증동물모형,용ICP전감우합등리자체발사광보법측정실험조화대조조고골중화혈청중개、린적함량.결과 실험조대서고골중적개、린함량명현저우대조조개、린적함량[Ca:(218.59±10.43)mg/L vs(253.32±7.54)mg/L;P:(127.82±3.71)mg/L vs(142.18±5.99)mg/L,P＜0.01],이혈청중적개、린함량명현고우대조조개、린적함량[Ca:(99.45±0.76)mg/L vs(97.56±0.80)mg/L;P:(67.68±1.63)mg/L vs(60.00±1.18)mg/L,P＜0.01].결론 고골중개、린함량적명현감소,대응혈청중개、린함량적증가시도치골질소송증적병인지일.
Objective To study the relationship between femur and serum calcium and phosphorus content in rat with osteoporosis. Methods We developed animal models with rat experienced bilateral oophorectomy and used inductively coupled plasma atomic emission spectrometry (ICP-AES) to determine calcium and phosphorus content in femur and serum of experimental group as well as control group. Results Calcium and phosphorus contents in femur in experimental group were significantly lower than that in control group[Ca: (218.59 ± 10.43) mg/L vs (253.32 ±7.54)mg/L;P:( 127.82 ±3.71 )mg/L vs ( 142. 18 ±5.99 ) mg/L, P ＜0. 01], but in serum experimental group it was significantly higher than that in control group [Ca: (99.45 ±0.76)mg/L vs (97.56±0.80) mg/L;P: (67.68 ± 1.63) mg/L vs (60.00 ± 1.18) mg/L,P ＜0. 01]. Conclusion Femur calcium and phosphorus levels were significantly reduced, which was related to the increase of serum calcium and phosphorus content, and it was one of the causes of osteoporosis.
