CAJ | 학술논문

患者,女,32岁,被诊断为纵隔未分化大细胞非霍奇金淋巴瘤,化疗后3a出现双眼悬浮物和右眼视力下降.眼科检查发现带有多发深在的左眼脉络膜病变的双侧全葡萄膜炎.眼窝电脑断层扫描显示两侧球后视神经部分加强和大块的视神经鞘.该患者接受眼窝受累区域放射治疗,累积剂量为30戈瑞.放射治疗8mo后,发展为黄斑部视网膜色素上皮脱离和右侧颞上和鼻下区眼底的深脉络膜视网膜变性.在脉络膜视网膜变性区边缘有玻璃体视网膜牵引迹象,从而路障激光在受累眼睛进行.双眼视力仍然6/6.视网膜色素上皮脱离可能是放射治疗非霍奇金淋巴瘤眼内转移时的并发症.至关重要的是提醒了眼科医生这个罕见的并发症.
환자,녀,32세,피진단위종격미분화대세포비곽기금림파류,화료후3a출현쌍안현부물화우안시력하강.안과검사발현대유다발심재적좌안맥락막병변적쌍측전포도막염.안와전뇌단층소묘현시량측구후시신경부분가강화대괴적시신경초.해환자접수안와수루구역방사치료,루적제량위30과서.방사치료8mo후,발전위황반부시망막색소상피탈리화우측섭상화비하구안저적심맥락막시망막변성.재맥락막시망막변성구변연유파리체시망막견인적상,종이로장격광재수루안정진행.쌍안시력잉연6/6.시망막색소상피탈리가능시방사치료비곽기금림파류안내전이시적병발증.지관중요적시제성료안과의생저개한견적병발증.
A 32-year-old lady, diagnosed with anaplastic large cell non-Hodgkin's lymphoma of the mediastinum, presented with bilateral floaters and reduced right eye vision 3 years post chemotherapy. Ophthalmic examination revealed bilateral panuveitis with multiple deep seated choroidal lesions in the left eye. Computed tomography scanning of the orbit showed enhancing and bulky optic nerve sheath at the retrobulbar part of both optic nerves. The patient was treated with involved field radiation therapy of the orbit, with cumulative dose of 30Gy. Eight months post radiation therapy, she developed retinal pigment epithelial detachment at the macula and deep chorioretinal degeneration at superotemporal and inferonasal regions of the right fundus. There was evidence of vitreoretinal traction at the margin of chorioretinal degeneration areas, thus barricade lasers were performed in the affected eye. Her visual acuity remains 6/6 in both eyes. Retinal pigment epithelial detachment is a possible complication of radiation therapy in non-Hodgkin's lymphoma with intraocular metastasis. It is essential to alert the managing ophthalmologists about this rare complication.