大理学院学报：综合版
大理學院學報：綜閤版
대이학원학보：종합판
Journal of Dali University
2011年
8期
50-51
,共2页
拉氧头孢钠%头孢吡肟%细菌性脑膜炎
拉氧頭孢鈉%頭孢吡肟%細菌性腦膜炎
랍양두포납%두포필우%세균성뇌막염
latamoxef sodium%cefepime%bacterial menigitis
目的：观察拉氧头孢钠治疗细菌性脑膜炎的临床疗效和安全性。方法：回顾性调查分析近5年我院治疗细菌性脑膜炎的病历,随即抽取拉氧头孢钠50mg/kg治疗组20例（A组）和头孢吡肟50 mg/kg对照组20例（B组）,1次/12 h,疗程均为5~14 d。比较两组临床疗效、细菌学改变及不良反应情况。结果：A、B两组的临床痊愈率分别为90.00%、85.00%,A、B两组的临床有效率分别为95.00%、90.00%,二者比较差异无统计学意义（P〉0.05）。结论：拉氧头孢钠治疗细菌性脑膜炎的疗效满意,不良反应少,药物安全性高,在新农合和城镇医保范围,可对医疗机构及患者取得双赢,值得在临床推广应用。
目的：觀察拉氧頭孢鈉治療細菌性腦膜炎的臨床療效和安全性。方法：迴顧性調查分析近5年我院治療細菌性腦膜炎的病歷,隨即抽取拉氧頭孢鈉50mg/kg治療組20例（A組）和頭孢吡肟50 mg/kg對照組20例（B組）,1次/12 h,療程均為5~14 d。比較兩組臨床療效、細菌學改變及不良反應情況。結果：A、B兩組的臨床痊愈率分彆為90.00%、85.00%,A、B兩組的臨床有效率分彆為95.00%、90.00%,二者比較差異無統計學意義（P〉0.05）。結論：拉氧頭孢鈉治療細菌性腦膜炎的療效滿意,不良反應少,藥物安全性高,在新農閤和城鎮醫保範圍,可對醫療機構及患者取得雙贏,值得在臨床推廣應用。
목적：관찰랍양두포납치료세균성뇌막염적림상료효화안전성。방법：회고성조사분석근5년아원치료세균성뇌막염적병력,수즉추취랍양두포납50mg/kg치료조20례（A조）화두포필우50 mg/kg대조조20례（B조）,1차/12 h,료정균위5~14 d。비교량조림상료효、세균학개변급불량반응정황。결과：A、B량조적림상전유솔분별위90.00%、85.00%,A、B량조적림상유효솔분별위95.00%、90.00%,이자비교차이무통계학의의（P〉0.05）。결론：랍양두포납치료세균성뇌막염적료효만의,불량반응소,약물안전성고,재신농합화성진의보범위,가대의료궤구급환자취득쌍영,치득재림상추엄응용。
Objective： To observe the clinical efficacy and safety of bacterial meningitis treated by latamoxef sodium.Methods： Retrospective investigation to the bacterial mengitis cases in our hospital in the past 5 years was taken.Forty cases were randomly selected and divided into the latamoxef sodium 50 mg/kg treatment group（group A） and the cefepime 50 mg/kg control group（group B）,each with 20 cases.Then the clinical efficacy,bacteriological changes and adverse reactions were compared between the two groups.Results： The clinical efficacy of group A and B was 95.00% and 90.00% respectively,without significant difference（P0.05）.Conclusion： Latamoxef sodium treating bacterial meningitis,which had higher efficacy,safety and less adverse reaction,could reach a win-win situation for both the medical institutions and the patients under the system of new rural cooperative medicare scheme and urban health insurance.It is wealthy of clinical application.
