中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2012年
8期
725-727
,共3页
王莹%王克永%张许来%吴庆%刘旺发%王莉%费龙才%黄英%吴丽敏%谢军
王瑩%王剋永%張許來%吳慶%劉旺髮%王莉%費龍纔%黃英%吳麗敏%謝軍
왕형%왕극영%장허래%오경%류왕발%왕리%비룡재%황영%오려민%사군
抑郁症%前瞻记忆%晚发性
抑鬱癥%前瞻記憶%晚髮性
억욱증%전첨기억%만발성
Depressive disorder%Prospective memory%Late onset
目的 研究晚发性抑郁症患者基于事件前瞻记忆(EBPM)和基于时间前瞻记忆(TBPM)的特征,明确基于事件前瞻记忆(EBPM)和基于时间前瞻记忆(TBPM)在晚发性抑郁症患者中的损害情况,探讨患者前瞻记忆与其临床症状的关系.方法 对32例晚发性抑郁症患者以及年龄、性别、受教育程度相匹配的30名正常对照者实施前瞻记忆测试,并用17项汉密尔顿抑郁量表评估患者的临床症状.结果 与正常对照组[EBPM:(3.07±0.87)分、TBPM:(2.67±0.92)分]相比,患者组的EBPM评分[(2.31±1.06)分]和TBPM评分[(2.03±0.93)分],差异有统计学意义(t=- 3.052,P＜0.01;t=- 2.695,P＜0.01).相关分析显示,患者EBPM和TBPM评分与汉密尔顿抑郁量表总分呈负相关(r=- 0.436,P=0.013;r=-0.467,P=0.007).结论 晚发性抑郁症患者基于事件前瞻记忆和基于时间前瞻记忆均存在损害,患者前瞻记忆与其临床症状存在相关性.
目的 研究晚髮性抑鬱癥患者基于事件前瞻記憶(EBPM)和基于時間前瞻記憶(TBPM)的特徵,明確基于事件前瞻記憶(EBPM)和基于時間前瞻記憶(TBPM)在晚髮性抑鬱癥患者中的損害情況,探討患者前瞻記憶與其臨床癥狀的關繫.方法 對32例晚髮性抑鬱癥患者以及年齡、性彆、受教育程度相匹配的30名正常對照者實施前瞻記憶測試,併用17項漢密爾頓抑鬱量錶評估患者的臨床癥狀.結果 與正常對照組[EBPM:(3.07±0.87)分、TBPM:(2.67±0.92)分]相比,患者組的EBPM評分[(2.31±1.06)分]和TBPM評分[(2.03±0.93)分],差異有統計學意義(t=- 3.052,P＜0.01;t=- 2.695,P＜0.01).相關分析顯示,患者EBPM和TBPM評分與漢密爾頓抑鬱量錶總分呈負相關(r=- 0.436,P=0.013;r=-0.467,P=0.007).結論 晚髮性抑鬱癥患者基于事件前瞻記憶和基于時間前瞻記憶均存在損害,患者前瞻記憶與其臨床癥狀存在相關性.
목적 연구만발성억욱증환자기우사건전첨기억(EBPM)화기우시간전첨기억(TBPM)적특정,명학기우사건전첨기억(EBPM)화기우시간전첨기억(TBPM)재만발성억욱증환자중적손해정황,탐토환자전첨기억여기림상증상적관계.방법 대32례만발성억욱증환자이급년령、성별、수교육정도상필배적30명정상대조자실시전첨기억측시,병용17항한밀이돈억욱량표평고환자적림상증상.결과 여정상대조조[EBPM:(3.07±0.87)분、TBPM:(2.67±0.92)분]상비,환자조적EBPM평분[(2.31±1.06)분]화TBPM평분[(2.03±0.93)분],차이유통계학의의(t=- 3.052,P＜0.01;t=- 2.695,P＜0.01).상관분석현시,환자EBPM화TBPM평분여한밀이돈억욱량표총분정부상관(r=- 0.436,P=0.013;r=-0.467,P=0.007).결론 만발성억욱증환자기우사건전첨기억화기우시간전첨기억균존재손해,환자전첨기억여기림상증상존재상관성.
Objective To investigate the event-based prospective memory (EBPM)and time-based prospective memory( TBPM )in late-onset depressive patients and to explore the relationships between prospective memory and depressive symptoms.Methods 32 late-onset depressive patients and 30 normal controls matched in age,gender and education were assessed with a neuropsychological battery of tests including EBPM and TBPM tasks.The patients were also assessed with Hamilton Depression Scale (HAMD).Results A statistically significant in EBPM was observed between patients with late-onset depression and normal controls (2.31 ± 1.06 vs 3.07± 0.87,t =- 3.052,P ＜ 0.01) and the same result in TBPM (2.03 ± 0.93 vs 2.67 ± 0.92,t =- 2.695,P ＜0.01 ).The negatively correlate was showed between the total scores of HAMD and EBPM ( r =- 0.436,P =0.013 ),TBPM ( r =- 0.467,P =0.007 ) in the patients.Conclusion The results suggest late-onset depressive patients impair both EBPM and TBPM.Prospective memory shows correlation with depressive symptoms in the patients.
