CAJ | 학술논문

目的探讨广州市及周边地区人群吸烟、饮酒、体重指数(body mass index,BMI)与胃肠癌的关系.方法纳入170例胃肠癌病例和166例健康人群,均来自广州及周边地区,年龄(±5岁)和性别相匹配.单因素卡方检验和多因素检验分析BMI、吸烟、饮酒与胃肠癌的关系.结果单因素卡方检验显示BMI、吸烟与胃肠癌无明显相关(P=0.46;P=0.88),饮酒与胃肠癌明显相关(P=0.03).多因素回归分析显示与不饮酒者相比,曾经饮酒者明显增加胃肠癌的风险(OR1.89,95%CI=1.08-3.33,P=0.03).结论饮酒是广州市及周边地区人群胃肠癌发生的独立危险因素,应加强卫生宣教.
목적 탐토엄주시급주변지구인군흡연、음주、체중지수(body mass index,BMI)여위장암적관계.방법 납입170례위장암병례화166례건강인군,균래자엄주급주변지구,년령(±5세)화성별상필배.단인소잡방검험화다인소검험분석BMI、흡연、음주여위장암적관계.결과 단인소잡방검험현시BMI、흡연여위장암무명현상관(P=0.46;P=0.88),음주여위장암명현상관(P=0.03).다인소회귀분석현시여불음주자상비,증경음주자명현증가위장암적풍험(OR1.89,95%CI=1.08-3.33,P=0.03).결론 음주시엄주시급주변지구인군위장암발생적독립위험인소,응가강위생선교.
Objective To investigate the association of the genesis of gastrointestinal cancer with tobacco smoking, alcohol intake, and body mass index(BMI)in Guangzhou and the surrounding areas. Methods 170 patients and 166 healthy controls from Guangzhou and the surrounding areas were included in this study. The patients and the controls were sex- and age-(within 5 years)matched. The association of gastrointestinal cancer with tobacco smoking, alcohol intake, and BMI were analyzed by single factor Chi-square test and Cox multivariate regression. Results Single factor Chi-square test showed BMI or tobacco smoking was not associated and the genesis of gastrointestinal cancer(P=0.46, P=0.88), while alcohol intake was associated with the genesis of gastrointestinal cancer(P=0.03). Cox multivariate regression showed former drinkers, as compared nondrinkers, had an increased risk of gastrointestinal cancer(adjusted OR 1.89, 95% CI = 1.08-3.33, P= 0.03). Conclusions Alcohol intake is an independent risk factor for gastrointestinal cancer in Guangzhou and the surrounding areas. Health education should be strengthened.