CAJ | 학술논문

目的评价不同时间窗内对动脉瘤患者进行血管内治疗的效果,探讨早期血管内治疗能否改善动脉瘤患者的预后.方法回顾性分析165例血管内治疗动脉瘤破裂出血患者的临床资料,按手术至发病时间不同分为3组:A组在出血后24h内进行治疗；B组在手术至出血时间为24 h-3d进行治疗；C组在3d后进行治疗.比较分析各组患者预后及主要并发症的发生率,包括再出血、脑积水及脑血管痉挛.结果早期及超早期治疗组再出血、脑血管痉挛及脑积水等主要并发症的发生率明显低于延期治疗组(P＜0.01)；延期治疗组患者脑血管痉挛发生的程度最严重,持续时间最长,早期治疗组次之,而在24h内得到治疗的患者,脑血管痉挛可以控制在较低水平,持续时间亦明显缩短；无论轻型或重型患者,早期治疗组预后评分均显著高于延期治疗组.结论早期血管内介入治疗能明显降低动脉瘤性蛛网膜下腔出血患者的并发症发生率,改善患者预后.
목적 평개불동시간창내대동맥류환자진행혈관내치료적효과,탐토조기혈관내치료능부개선동맥류환자적예후.방법 회고성분석165례혈관내치료동맥류파렬출혈환자적림상자료,안수술지발병시간불동분위3조:A조재출혈후24h내진행치료；B조재수술지출혈시간위24 h-3d진행치료；C조재3d후진행치료.비교분석각조환자예후급주요병발증적발생솔,포괄재출혈、뇌적수급뇌혈관경련.결과조기급초조기치료조재출혈、뇌혈관경련급뇌적수등주요병발증적발생솔명현저우연기치료조(P＜0.01)；연기치료조환자뇌혈관경련발생적정도최엄중,지속시간최장,조기치료조차지,이재24h내득도치료적환자,뇌혈관경련가이공제재교저수평,지속시간역명현축단；무론경형혹중형환자,조기치료조예후평분균현저고우연기치료조.결론 조기혈관내개입치료능명현강저동맥류성주망막하강출혈환자적병발증발생솔,개선환자예후.
Objective To evaluate the effects of endovascular embolization treatment for intracranial aneurysms in different time.Methods To respectively analyse the clinical data of 165 cases of ruptured intracranial aneurysm treated by endovascular treatment.The patients were divided into 3 groups accrodding to the time of treatment,endovascular reatments were stated within 24 h in group A,3 d in group B and after 3 d in group C.The outcomes and complications including rebleeding,vasospasm and hydrocephala of 3 groups were compared.Results The incidence of rebleeding,vasospasm and hydrocephala in group A and B were lower than that in group C ( P ＜0.01 ).Vasospasm in group C was most severe.The GOS score was highest in group A and lowest in group C.Conclusion Endovascular embolization treatment is a safe and effective method for treatment of intracranial aneurysm.The timing of treatment is a major factor for technical success.