中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2008年
3期
282-284
,共3页
张春阳%张俊朋%苏里%王伟志%张安龙%张宁%董艳芳%冯士军%张震军%石瑞成
張春暘%張俊朋%囌裏%王偉誌%張安龍%張寧%董豔芳%馮士軍%張震軍%石瑞成
장춘양%장준붕%소리%왕위지%장안룡%장저%동염방%풍사군%장진군%석서성
颅骨缺损%生长和发育%形态学
顱骨缺損%生長和髮育%形態學
로골결손%생장화발육%형태학
Skull defect%Growth and development%Morphology
目的 探讨未发育成熟缺损颅骨后期生长的形态学变化.方法 20只2月龄小尾寒羊(雌雄各半)采用随机数字表法分为2组,手术组、对照组各10只.将手术组幼羊颅骨顶部手术去除造成直径4 cm的颅骨缺损,观察后期颅骨及缺损边缘的骨生长情况,并与对照组(不做任何处理,与手术组在相同环境下饲养)比较各项指标.结果 手术组2只分别死于并发症及外伤,2只出现颅骨缺损区下方脑组织萎缩,并伴有神经精神症状.骨窗边缘有新生骨向心性生长,所有缺损区面积均变小.但新生骨骨质薄弱.另有1只骨窗边缘新生骨有部分呈外翻性畸形生长.其余指标与对照组对比无显著性差异.结论 幼羊颅骨缺损后未出现颅骨发育畸形,其骨窗可因新生骨生长而变小,缺损未完全愈合,也不足以达到正常强度,不能有效起到对脑组织的保护作用.
目的 探討未髮育成熟缺損顱骨後期生長的形態學變化.方法 20隻2月齡小尾寒羊(雌雄各半)採用隨機數字錶法分為2組,手術組、對照組各10隻.將手術組幼羊顱骨頂部手術去除造成直徑4 cm的顱骨缺損,觀察後期顱骨及缺損邊緣的骨生長情況,併與對照組(不做任何處理,與手術組在相同環境下飼養)比較各項指標.結果 手術組2隻分彆死于併髮癥及外傷,2隻齣現顱骨缺損區下方腦組織萎縮,併伴有神經精神癥狀.骨窗邊緣有新生骨嚮心性生長,所有缺損區麵積均變小.但新生骨骨質薄弱.另有1隻骨窗邊緣新生骨有部分呈外翻性畸形生長.其餘指標與對照組對比無顯著性差異.結論 幼羊顱骨缺損後未齣現顱骨髮育畸形,其骨窗可因新生骨生長而變小,缺損未完全愈閤,也不足以達到正常彊度,不能有效起到對腦組織的保護作用.
목적 탐토미발육성숙결손로골후기생장적형태학변화.방법 20지2월령소미한양(자웅각반)채용수궤수자표법분위2조,수술조、대조조각10지.장수술조유양로골정부수술거제조성직경4 cm적로골결손,관찰후기로골급결손변연적골생장정황,병여대조조(불주임하처리,여수술조재상동배경하사양)비교각항지표.결과 수술조2지분별사우병발증급외상,2지출현로골결손구하방뇌조직위축,병반유신경정신증상.골창변연유신생골향심성생장,소유결손구면적균변소.단신생골골질박약.령유1지골창변연신생골유부분정외번성기형생장.기여지표여대조조대비무현저성차이.결론 유양로골결손후미출현로골발육기형,기골창가인신생골생장이변소,결손미완전유합,야불족이체도정상강도,불능유효기도대뇌조직적보호작용.
Obiective To study the morphological changes of immature defected skull in later growth. Methods Twenty 2-month small-tail Han sheep (female/male ratio 1:1) were randomly divided into operation group(n=10)and control group(n=10).In the former,the parietal skull of 4 cm in diameter was removed in each sheep so as to observe the growth condition of defected bone.In the latter,the sheep were kept in the same envimnmem as the operation group,but without any operation.Results In the operation group, 2 sheep died from complications and trauma, 2 suffered from cerebral atrophy right under defected area,accompanied with psychiatric symptom,and 1 developed everted growth on the margin of bone window;in the others,the margin of bone window appeared afferent growth,which made the defected area smaller, but the new bone was thin and weak relatively. The rest indexes were not different between the 2 groups. Conclusions Skull defect won't lead to skull development malfomlation, and it can be repaired to some extent by bone growth, but the growth can not close completely the defect and make it strong enough for protecting the brain tissue.
