CAJ | 학술논문

目的比较冻融胚胎移植(FET)与新鲜胚胎移植的多胎妊娠率,分析多胎妊娠的相关因素,探讨移植不同数目的胚胎对冻胚移植周期临床妊娠率的影响.方法对经FET获得的1235例临床妊娠与经新鲜胚胎移植获得的1561例临床妊娠中的多胎妊娠进行回顾性分析.结果多胎妊娠与移植周期(FET或新鲜胚胎移植)无关,而与女方的年龄、移植胚胎数、以及卵裂期胚胎或囊胚移植密切相关.在相同年龄段移植相同数目卵裂期胚胎时,FET 与新鲜胚胎移植的多胎妊娠率差异无统计学意义,增加移植胚胎数主要是增加了三胎妊娠率.＜35岁的妇女移植2个冻融胚胎的临床妊娠率可达36.1%.结论多胎妊娠率与冻胚移植或新鲜胚胎移植无关.＜35岁的妇女移植2个冻融胚胎可以取得较好的妊娠率,同时可以降低FET周期的三胎妊娠率.
목적 비교동융배태이식(FET)여신선배태이식적다태임신솔,분석다태임신적상관인소,탐토이식불동수목적 배태대동배이식주기림상임신솔적영향.방법 대경FET획득적1235례림상임신여경신선배태이식획득적1561례림상임신중적다태임신진행회고성분석.결과 다태임신여이식주기(FET혹신선배태이식)무관,이여녀방적년령、이식배태수、이급란렬기배태혹낭배이식밀절상관.재상동년령단이식상동수목란렬기배태시,FET 여신선배태이식적다태임신솔차이무통계학의의,증가이식배태수주요시증가료삼태임신솔.＜35세적부녀이식2개동융배태적림상임신솔가체36.1%.결론 다태임신솔여동배이식혹신선배태이식무관.＜35세적부녀이식2개동융배태가이취득교호적임신솔,동시가이강저FET주기적삼태임신솔.
Objective To compare the multiple pregnancy rates of frozen-thawed embryos transfer (FET)or fresh embryos transfer,analyze the factors related to multiple pregnancies after IVF and study pregnancy rates with different number of embryos transferred in FET cycle.Methods A retrospective analysis was performed upon multiple pregnancies from 1235 and 1561 clinical pregnancies conceived by FET or fresh embryo transfers.Results No correlation Was found between fresh or cryopreserved embryos transfer and multiple pregnancy rates.There were significant effects of woman's age,number of embryos transferred and stage of embryos upon multiple pregnancy rates.When the same number of cleavage-stage embryos Was transferred to women with the same age,twin pregnancy rate or triplet pregnancy rate was the same between FET and fresh cycles.Triplet pregnancy rate with three embryos transferred was significantly higher than that of two embryos transferred.In women under 35 years old,the pregnancy rate with two embryos transferred reached 36.1%.Conclusion Frozen-thawed embryos or fresh embryos transfer has no effect upon the multiple pregnancy rate.Women under 35 years old can achieve acceptable pregnancy rates when two cryopreserved embryos are transferred.It is helpful to reduce the triplet pregnancy rate.