中华小儿外科杂志
中華小兒外科雜誌
중화소인외과잡지
CHINESE JOURNAL OF PEDIATRIC SURGERY
2012年
2期
105-108
,共4页
文建国%李燕%张茜%王亚仑%陈燕%杨黎%娄安锋%张艳%任川%李一冬
文建國%李燕%張茜%王亞崙%陳燕%楊黎%婁安鋒%張豔%任川%李一鼕
문건국%리연%장천%왕아륜%진연%양려%루안봉%장염%임천%리일동
高胆红素血症%新生儿%排尿
高膽紅素血癥%新生兒%排尿
고담홍소혈증%신생인%배뇨
Hyperbilirubinemia%Neonatal%Urination
目的 探讨不同程度高胆红素血症对新生儿排尿方式的影响.方法 选取出生后4～15d确诊为高胆红素血症新生儿33例,根据不同血清总胆红素(Tbil)水平,分为轻中度高胆组(mild to moderate hyperbilirubinemia,MHB)和重度高胆组(severe hyperbilirubinemia,SHB).其中MHB组18例,胎龄(38.6±2.1)周,体重(3.1±0.3)kg; SHB组15例,胎龄(38.9±1.8)周,体重(3.4±0.4) kg.连续4h观察新生儿排尿,记录排尿次数、每次尿量、残余尿量、排尿时觉醒状态.同时选取胆红素水平正常新生儿19例为对照组.比较各组参数的差异.结果 SHB组排尿次数和残余尿量分别为(3.3±1.1)次和(1.8±0.5) ml,显著高于正常组[(2.7±0.8)次和(1.3±0.8)ml]和MHB组[(2.7±0.8)次,(1.4±(0.7) ml],(P＜0.05)；平均每次排尿量(23.1±8.3)ml明显低于正常组(27.8±7.3) ml和MHB组(26.9±5.6) ml,(P＜0.05).排尿时清醒状态百分比在三组之间无统计学差异(P＞0.05).结论 SHB新生儿排尿方式明显改变.排尿方式的改变是否与重度高胆红素血症影响新生儿排尿中枢有关有待进一步研究.
目的 探討不同程度高膽紅素血癥對新生兒排尿方式的影響.方法 選取齣生後4～15d確診為高膽紅素血癥新生兒33例,根據不同血清總膽紅素(Tbil)水平,分為輕中度高膽組(mild to moderate hyperbilirubinemia,MHB)和重度高膽組(severe hyperbilirubinemia,SHB).其中MHB組18例,胎齡(38.6±2.1)週,體重(3.1±0.3)kg; SHB組15例,胎齡(38.9±1.8)週,體重(3.4±0.4) kg.連續4h觀察新生兒排尿,記錄排尿次數、每次尿量、殘餘尿量、排尿時覺醒狀態.同時選取膽紅素水平正常新生兒19例為對照組.比較各組參數的差異.結果 SHB組排尿次數和殘餘尿量分彆為(3.3±1.1)次和(1.8±0.5) ml,顯著高于正常組[(2.7±0.8)次和(1.3±0.8)ml]和MHB組[(2.7±0.8)次,(1.4±(0.7) ml],(P＜0.05)；平均每次排尿量(23.1±8.3)ml明顯低于正常組(27.8±7.3) ml和MHB組(26.9±5.6) ml,(P＜0.05).排尿時清醒狀態百分比在三組之間無統計學差異(P＞0.05).結論 SHB新生兒排尿方式明顯改變.排尿方式的改變是否與重度高膽紅素血癥影響新生兒排尿中樞有關有待進一步研究.
목적 탐토불동정도고담홍소혈증대신생인배뇨방식적영향.방법 선취출생후4～15d학진위고담홍소혈증신생인33례,근거불동혈청총담홍소(Tbil)수평,분위경중도고담조(mild to moderate hyperbilirubinemia,MHB)화중도고담조(severe hyperbilirubinemia,SHB).기중MHB조18례,태령(38.6±2.1)주,체중(3.1±0.3)kg; SHB조15례,태령(38.9±1.8)주,체중(3.4±0.4) kg.련속4h관찰신생인배뇨,기록배뇨차수、매차뇨량、잔여뇨량、배뇨시각성상태.동시선취담홍소수평정상신생인19례위대조조.비교각조삼수적차이.결과 SHB조배뇨차수화잔여뇨량분별위(3.3±1.1)차화(1.8±0.5) ml,현저고우정상조[(2.7±0.8)차화(1.3±0.8)ml]화MHB조[(2.7±0.8)차,(1.4±(0.7) ml],(P＜0.05)；평균매차배뇨량(23.1±8.3)ml명현저우정상조(27.8±7.3) ml화MHB조(26.9±5.6) ml,(P＜0.05).배뇨시청성상태백분비재삼조지간무통계학차이(P＞0.05).결론 SHB신생인배뇨방식명현개변.배뇨방식적개변시부여중도고담홍소혈증영향신생인배뇨중추유관유대진일보연구.
Objective To explore the effect of different degree of hyperbilirubinemia on the voiding pattern of newborn.Methods Four-hour voiding observations were performed on 52 newborns with the gestational ages ranged from 37 to 42 weeks.Of whom,18 had mild to moderate hyperbilirubinemia (MHB) [blood total bilirubin level (Tbil) ranged from 221 μtmol/l to 342μmol/l] ; 15 had severe hyperbilirubinemia (SHB) (Tbil ＞342μmol/l).Nineteen babies had normal bilirubin level (NB) (Tbil ＜221 μmol/l).The voiding frequency (VF),voiding volume (VV),post-void residual volume (PRV),and percentage of awake voiding (AVP) of every infant from 8AM to 12AM were recorded.A total of 328 voids were observed in this study.Results The VF and PVR [ (3.3 ± 1.1 ) times,( 1.8 ± 0.5) ml] of SHB is higher than NB [(2.7 ± 0.8) times,(1.3 ± 0.8) ml] and MHB [(2.7 ± 0.8) times,(1.4 ±0.7) ml] (P＜0.05).The VV of SHB(23.1 ± 8.3) ml is lower than NB(27.8 ± 7.3) ml and MHB (26.9 ± 5.6) ml(P＜0.05).There is no difference of AVP among 3 groups.Conclusions There is a significant change of voiding pattern in newborn with severe hyperbilirubinemia,suggesting that severe hyperbilirubinemia has an effect on the nerve micturition center.
