中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2011年
13期
40-41
,共2页
丙泊酚%瑞芬太尼%氯胺酮%唇腭裂修补术
丙泊酚%瑞芬太尼%氯胺酮%脣腭裂脩補術
병박분%서분태니%록알동%진악렬수보술
Propofol%Remifentanil%Ketamine%Cleft lip and palate repairment
目的 比较丙泊酚、瑞芬太尼和丙泊酚、氯胺酮用于小儿唇腭裂手术麻醉的效果和安全性.方法 选择80例择期行唇腭裂修复术的患儿为研究对象,随机分为两组,PR组40例,采用丙泊酚和瑞芬太尼麻醉;K组40例,采用丙泊酚和氯胺酮麻醉,记录两组患儿在麻醉诱导前(T1)、诱导插管时(T2)、手术开始(T3)、拔管时(T4)血流动力学的指标.记录术毕患儿的苏醒情况、拔管时间及恶心呕吐和气道并发症的发生情况.结果 两组患儿的插管反应率比较差异无统计学意义(P＞0.05).PR组的血压、心率较K组平稳(P＜0.05);停药后拔管时间,PR组较K组明显缩短(P＜0.05);恶心呕吐的发生率两组比较差异无统计学意义(P＞0.05),但苏醒时躁动和哭闹的发生率,K组高于PR组(P＜0.05).结论 瑞芬太尼复合丙泊酚麻醉用于小儿先天性唇腭裂修复术,可使血流动力学稳定,苏醒迅速,并发症少,是一种安全有效的麻醉方法.
目的 比較丙泊酚、瑞芬太尼和丙泊酚、氯胺酮用于小兒脣腭裂手術痳醉的效果和安全性.方法 選擇80例擇期行脣腭裂脩複術的患兒為研究對象,隨機分為兩組,PR組40例,採用丙泊酚和瑞芬太尼痳醉;K組40例,採用丙泊酚和氯胺酮痳醉,記錄兩組患兒在痳醉誘導前(T1)、誘導插管時(T2)、手術開始(T3)、拔管時(T4)血流動力學的指標.記錄術畢患兒的囌醒情況、拔管時間及噁心嘔吐和氣道併髮癥的髮生情況.結果 兩組患兒的插管反應率比較差異無統計學意義(P＞0.05).PR組的血壓、心率較K組平穩(P＜0.05);停藥後拔管時間,PR組較K組明顯縮短(P＜0.05);噁心嘔吐的髮生率兩組比較差異無統計學意義(P＞0.05),但囌醒時躁動和哭鬧的髮生率,K組高于PR組(P＜0.05).結論 瑞芬太尼複閤丙泊酚痳醉用于小兒先天性脣腭裂脩複術,可使血流動力學穩定,囌醒迅速,併髮癥少,是一種安全有效的痳醉方法.
목적 비교병박분、서분태니화병박분、록알동용우소인진악렬수술마취적효과화안전성.방법 선택80례택기행진악렬수복술적환인위연구대상,수궤분위량조,PR조40례,채용병박분화서분태니마취;K조40례,채용병박분화록알동마취,기록량조환인재마취유도전(T1)、유도삽관시(T2)、수술개시(T3)、발관시(T4)혈류동역학적지표.기록술필환인적소성정황、발관시간급악심구토화기도병발증적발생정황.결과 량조환인적삽관반응솔비교차이무통계학의의(P＞0.05).PR조적혈압、심솔교K조평은(P＜0.05);정약후발관시간,PR조교K조명현축단(P＜0.05);악심구토적발생솔량조비교차이무통계학의의(P＞0.05),단소성시조동화곡료적발생솔,K조고우PR조(P＜0.05).결론 서분태니복합병박분마취용우소인선천성진악렬수복술,가사혈류동역학은정,소성신속,병발증소,시일충안전유효적마취방법.
Objective To compare the anesthetic effects and safety of propofol combined with remifentanil and propofol combined with ketamine when used for cleft lip and palate repairment in children. Methods Eighty children that have cleft lip and palate repair surgery were randomly divided into propofol, remifentanil anaesthesia group(PR group, n=40)and ketamine, propofol anaesthesia group (K group, n=40). Hemodmnamics indexes were detected and recorded at the following sites time: before the induction(T1), intubation(T2), before operation(T3), extubation(T4). The time to extubation, incidence of restlessness, postoperative nansea and vomiting and the complication of airway were observed at the same time. Results There were no significant differences between the two groups when the incidcnce rate of intubation response and postoperative nansea and vomiting were compared(P>0.05). The hemodynamic changes were more stable in PR group than that in K group(P<0.05). The time of creasing drays to restoration of automatic respiration, openning eyes, and extubation were shorter in PR group(P<0.05).The incidence of agitation after surgery in K group was significantly higher than that in PR group (P<0.05). Conclusions Remifentanil combined with propofol can be applied to the repairment of cleft lip and palate in infants because of its safety and validity.
