CAJ | 학술논문

目的评价手术治疗对结直肠癌肺转移生存率的影响.方法回顾分析2005年1月至2008年10月上海复旦大学中山医院收治的77例结直肠癌肺转移患者的临床资料,其中30例接受手术切除,分析手术治疗对患者生存率的影响.结果本组同时性肺转移38例,行手术治疗2例,平均生存时间25个月;未行手术治疗36例,中位生存时间18个月,两者差异无统计学意义(P=0.33).异时性肺转移39例,行手术治疗28例,未手术者11例,手术组患者1、3年生存率分别为93.3%和58.5%,中位生存时间为26.7个月;未手术组患者的1、3年生存率分别为38.8%和19.1%,中位生存时间8个月;两者比较,差异有统计学意义(P=0.004).结论手术治疗结直肠癌肺转移可以提高患者生存率.
목적 평개수술치료대결직장암폐전이생존솔적영향.방법 회고분석2005년1월지2008년10월상해복단대학중산의원수치적77례결직장암폐전이환자적림상자료,기중30례접수수술절제,분석수술치료대환자생존솔적영향.결과 본조동시성폐전이38례,행수술치료2례,평균생존시간25개월;미행수술치료36례,중위생존시간18개월,량자차이무통계학의의(P=0.33).이시성폐전이39례,행수술치료28례,미수술자11례,수술조환자1、3년생존솔분별위93.3%화58.5%,중위생존시간위26.7개월;미수술조환자적1、3년생존솔분별위38.8%화19.1%,중위생존시간8개월;량자비교,차이유통계학의의(P=0.004).결론 수술치료결직장암폐전이가이제고환자생존솔.
Objective To evaluate the survival rate after pulmonary resection for metastatic colorectal cancer (CRC). Methods Clinical data of 77 patients with pulmonary metastasis from CRC between January 2005 and October 2008 in the Zhongshan Hospital, Fudan University were retrospectively analyzed. Results There were 38 patients with synchronous pulmonary metastasis, of whom 2 underwent resection for pulmonary metastasis. The median survival time of two groups was 25 months and 18 months, which was not significantly different (P=0.33). There were 39 cases of metachronous pulmonary metastasis, of whom 28 received pulmonary metastasis resection. The 1-year and 3-year survival rates of 2 groups were 93.3% and 58.5%, and 38.8% and 19.1%, respectively. The median survival time of two groups was 26.7 months and 8 months, and the difference was statistically significant (P=0.004). Conclusion Surgical resection can improve the survival rate in patients with pulmonary metastasis from colorectal cancer.