中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2011年
3期
224-228
,共5页
王莹莹%李强%于萍%高萍%邬艳慧%崔璨%王薇%陈莉丽%乔虹%王丽宏%项莹%张众%张巾超
王瑩瑩%李彊%于萍%高萍%鄔豔慧%崔璨%王薇%陳莉麗%喬虹%王麗宏%項瑩%張衆%張巾超
왕형형%리강%우평%고평%오염혜%최찬%왕미%진리려%교홍%왕려굉%항형%장음%장건초
实时动态血糖监测系统%空腹时段%餐后时段%准确性%血糖波动
實時動態血糖鑑測繫統%空腹時段%餐後時段%準確性%血糖波動
실시동태혈당감측계통%공복시단%찬후시단%준학성%혈당파동
Real-time continuous monitoring system%Fasting periods%Postprandial periods%Accuracy%Glucose excursion
目的 研究实时动态血糖监测系统(real-time continuous monitoring system,RT-CGMS)在不同时段检测的准确性及其与血糖波动的关系.方法 33例1型或2型糖尿病患者佩戴RT-CGMS5 d,每天测定7次毛细血管血糖值.应用相关分析、误差栅格分析(EGA)、Bland-Altman分析方法研究RT-CGMS在不同时段和总体水平与毛细血管血糖相关性、准确性和一致性;计算不同时段和总体水平的平均血糖波动幅度(MAGE)及血糖波动频率(FGE).结果 (1)RT-CGMS在空腹时段、餐后时段和总体水平与毛细血管血糖相关系数分别为0.94、0.92和0.93(均P<0.01).(2)EGA显示,空腹时段、餐后时段和总体水平分别有98.82%、98.39%和98.64%的点落在A区和B区;1.18%、1.61%和1.36%的点在D区;没有点落在C区和E区.(3)RT-CGMS在空腹时段、餐后时段和总体水平与毛细血管血糖的一致性良好.(4)空腹时段、餐后时段和总体水平的MAGE分别为(3.57±2.66)、(4.07±3.09)和(4.02±3.04)mmol/L(P>0.05);FGE分别为(0±0.5)、(3±1)和(1±3)次/d(P<0.01).结论 RT-CGMS在空腹时段检测准确性高于餐后时段和总体水平;餐后时段血糖波动频率高于空腹时段和总体水平.
目的 研究實時動態血糖鑑測繫統(real-time continuous monitoring system,RT-CGMS)在不同時段檢測的準確性及其與血糖波動的關繫.方法 33例1型或2型糖尿病患者珮戴RT-CGMS5 d,每天測定7次毛細血管血糖值.應用相關分析、誤差柵格分析(EGA)、Bland-Altman分析方法研究RT-CGMS在不同時段和總體水平與毛細血管血糖相關性、準確性和一緻性;計算不同時段和總體水平的平均血糖波動幅度(MAGE)及血糖波動頻率(FGE).結果 (1)RT-CGMS在空腹時段、餐後時段和總體水平與毛細血管血糖相關繫數分彆為0.94、0.92和0.93(均P<0.01).(2)EGA顯示,空腹時段、餐後時段和總體水平分彆有98.82%、98.39%和98.64%的點落在A區和B區;1.18%、1.61%和1.36%的點在D區;沒有點落在C區和E區.(3)RT-CGMS在空腹時段、餐後時段和總體水平與毛細血管血糖的一緻性良好.(4)空腹時段、餐後時段和總體水平的MAGE分彆為(3.57±2.66)、(4.07±3.09)和(4.02±3.04)mmol/L(P>0.05);FGE分彆為(0±0.5)、(3±1)和(1±3)次/d(P<0.01).結論 RT-CGMS在空腹時段檢測準確性高于餐後時段和總體水平;餐後時段血糖波動頻率高于空腹時段和總體水平.
목적 연구실시동태혈당감측계통(real-time continuous monitoring system,RT-CGMS)재불동시단검측적준학성급기여혈당파동적관계.방법 33례1형혹2형당뇨병환자패대RT-CGMS5 d,매천측정7차모세혈관혈당치.응용상관분석、오차책격분석(EGA)、Bland-Altman분석방법연구RT-CGMS재불동시단화총체수평여모세혈관혈당상관성、준학성화일치성;계산불동시단화총체수평적평균혈당파동폭도(MAGE)급혈당파동빈솔(FGE).결과 (1)RT-CGMS재공복시단、찬후시단화총체수평여모세혈관혈당상관계수분별위0.94、0.92화0.93(균P<0.01).(2)EGA현시,공복시단、찬후시단화총체수평분별유98.82%、98.39%화98.64%적점락재A구화B구;1.18%、1.61%화1.36%적점재D구;몰유점락재C구화E구.(3)RT-CGMS재공복시단、찬후시단화총체수평여모세혈관혈당적일치성량호.(4)공복시단、찬후시단화총체수평적MAGE분별위(3.57±2.66)、(4.07±3.09)화(4.02±3.04)mmol/L(P>0.05);FGE분별위(0±0.5)、(3±1)화(1±3)차/d(P<0.01).결론 RT-CGMS재공복시단검측준학성고우찬후시단화총체수평;찬후시단혈당파동빈솔고우공복시단화총체수평.
Objective To study the accuracy of real-time continuous monitoring system (RT-CGMS) at different stages and its association with glucose excursion. Methods Totally 33 patients with type 1 diabetes or type 2diabetes were under surveillance of RT-CGMS for 5 d. Capillary glucose values were measured 7 times daily.Correlation coefficient, error grid analysis (EGA), and Bland-Altman analysis methods were used to assess the correlation, accuracy and agreement of RT-CGMS at different stages and in general level; The mean amplitude of glucose excursion (MAGE) and the frequency of glucose excursion ( FGE ) were also calculated. Results ( 1 ) The correlation coefficient of RT-CGMS with capillary glucose values at fasting, postprandial stages, and in general level were 0.94,0.92, and 0.93 respectively( P<0.01 ). (2) EGA showed that 98.82%, 98.39%, and 98.64% of the results fell in the A and B zones and 1. 18%, 1.61%, and 1.36% fell in the D zone respectively at fasting,postprandial stages, and in general level. There is no result fell in C and E zones. ( 3 ) The agreement analysis showed that RT-CGMS readings were in close agreement with capillary glucose values at fasting, postprandial periods, and in general level. (4)The MAGE at fasting, postprandial periods, and in general level were (3.57±2.66), (4.07±3.09), and (4. 02 ±3.04) mmol/L (P>0. 05), (0±0. 5), (3± 1), and( 1 ±3) d for FGE (P<0. 01 ).Conclusion RT-CGMS at fasting stage has higher accuracy than postprandial stage and general level, FGE at fasting stage is higher than postprandial stage and general level.