中华围产医学杂志
中華圍產醫學雜誌
중화위산의학잡지
CHINESE JOURNAL OF PERINATAL MEDICINE
2008年
2期
96-100
,共5页
单红梅%蔡威%汤庆娅%曹云%施婴婴%方炳华
單紅梅%蔡威%湯慶婭%曹雲%施嬰嬰%方炳華
단홍매%채위%탕경아%조운%시영영%방병화
婴儿%极低出生体重%生长障碍%营养支持
嬰兒%極低齣生體重%生長障礙%營養支持
영인%겁저출생체중%생장장애%영양지지
Infant,very low birth weight%Growth disorders%Nutritional support
目的 评价上海市极低出生体重儿(very low birth weight infant,VLBWI)出生时胎儿生长受限(fetal growth restriction,FGR)和出院时宫外生长发育迟缓(extrauterine growth retardation,EUGR)的发生率并分析营养支持的影响. 方法 收集上海市5家医院126例VLBWI临床资料,分析FGR和EUGR发生率,比较EUGR和非EUGR患儿间的生长发育和营养支持指标.并采用Logistic回归分析EUGR危险因素. 结果 以体重评价,FGR与EUGR发生率分别为53.2%和80.2%,以头围评价为55.6%和46.7%;FGR和EUGR的发生率均随体重减少而增加;以体重评价时,FGR和EuGR发生率随胎龄增加而增加.EUGR组出生胎龄为(32.2±1.8)周,脂肪乳剂为(1.4±0.5)g/(kg·d),高于非EUGR组[分别为(30.9±2.7)周和(0.9±0.2)g/(kg·d)];而出生体重为(1330±156)g,低于非EUGR组[(1380±90)g].Logistic回归分析发现首次应用EN的日龄(OR=0.264,95%CI 0.079～0.876,P=0.04)和PN配方葡萄糖用量(OR=0.029,95%CI 0.001～O.861,P=0.048)是EUGR的危险因素. 结论 出生体重越低,EUGR发生率越高;目前的营养策略仍存在缺陷,不能满足VLBWI生后的营养需求.
目的 評價上海市極低齣生體重兒(very low birth weight infant,VLBWI)齣生時胎兒生長受限(fetal growth restriction,FGR)和齣院時宮外生長髮育遲緩(extrauterine growth retardation,EUGR)的髮生率併分析營養支持的影響. 方法 收集上海市5傢醫院126例VLBWI臨床資料,分析FGR和EUGR髮生率,比較EUGR和非EUGR患兒間的生長髮育和營養支持指標.併採用Logistic迴歸分析EUGR危險因素. 結果 以體重評價,FGR與EUGR髮生率分彆為53.2%和80.2%,以頭圍評價為55.6%和46.7%;FGR和EUGR的髮生率均隨體重減少而增加;以體重評價時,FGR和EuGR髮生率隨胎齡增加而增加.EUGR組齣生胎齡為(32.2±1.8)週,脂肪乳劑為(1.4±0.5)g/(kg·d),高于非EUGR組[分彆為(30.9±2.7)週和(0.9±0.2)g/(kg·d)];而齣生體重為(1330±156)g,低于非EUGR組[(1380±90)g].Logistic迴歸分析髮現首次應用EN的日齡(OR=0.264,95%CI 0.079～0.876,P=0.04)和PN配方葡萄糖用量(OR=0.029,95%CI 0.001～O.861,P=0.048)是EUGR的危險因素. 結論 齣生體重越低,EUGR髮生率越高;目前的營養策略仍存在缺陷,不能滿足VLBWI生後的營養需求.
목적 평개상해시겁저출생체중인(very low birth weight infant,VLBWI)출생시태인생장수한(fetal growth restriction,FGR)화출원시궁외생장발육지완(extrauterine growth retardation,EUGR)적발생솔병분석영양지지적영향. 방법 수집상해시5가의원126례VLBWI림상자료,분석FGR화EUGR발생솔,비교EUGR화비EUGR환인간적생장발육화영양지지지표.병채용Logistic회귀분석EUGR위험인소. 결과 이체중평개,FGR여EUGR발생솔분별위53.2%화80.2%,이두위평개위55.6%화46.7%;FGR화EUGR적발생솔균수체중감소이증가;이체중평개시,FGR화EuGR발생솔수태령증가이증가.EUGR조출생태령위(32.2±1.8)주,지방유제위(1.4±0.5)g/(kg·d),고우비EUGR조[분별위(30.9±2.7)주화(0.9±0.2)g/(kg·d)];이출생체중위(1330±156)g,저우비EUGR조[(1380±90)g].Logistic회귀분석발현수차응용EN적일령(OR=0.264,95%CI 0.079～0.876,P=0.04)화PN배방포도당용량(OR=0.029,95%CI 0.001～O.861,P=0.048)시EUGR적위험인소. 결론 출생체중월저,EUGR발생솔월고;목전적영양책략잉존재결함,불능만족VLBWI생후적영양수구.
Objective To assess the incidences of fetal growth retardation(FGR)and extrauterine growth retardation(EUGR)in very low birth weight infants(VLBWIs)and nutritional effency on EUGR. Methods Data of 126 VLBWIs incharged in 5 hospitals from January 1.2003 to December 31.2004 were reviewed.The risk factors for extrauterine growth retardation were estimated with logistic regression model. Results Assessing by weight and head circumference,the incidence of FGR was 53.2%and 55.6%,and the incidence of EUGR was 80.2%and 46.7%,respectively.The birth weight of EUGR group was(1330±156)g,lower than that of non-EUGR group[(1380±90)g].The age for initial using enteral nutrinion(OR=0.264,95%CI 0.079-0.876,P=0.04)and glucose intake in PN (OR=0.029,95%CI 0.001-0.861,P=0.048)were the risk factors of EUGR. Conclusions The incidence of EUGR increased with the birth weight decreased.Current nutritional support could not prevent extrauterine growth retardation in VLBWIs.
