CAJ | 학술논문

目的　探讨尿路上皮多器官癌发生的特点和机理。　方法　对527例移行细胞癌中42例尿路上皮多器官癌病例进行临床分析并结合文献进行讨论。　结果　42例尿路上皮多器官癌同期发生者17例，相继发生者25例，后者顺尿流方向发生者20例，逆尿流方向发生者5例。相继发生多器官癌病例，不同器官罹患癌间期3个月～19年，<2年者18例，2～3年者3例，>3年者仅4例。绝大多数尿路上皮多器官癌病例肿瘤病理分级具有一致性。　结论　肿瘤细胞种植可能是尿路上皮多器官癌发生的重要原因。
목적　탐토뇨로상피다기관암발생적특점화궤리。　방법　대527례이행세포암중42례뇨로상피다기관암병례진행림상분석병결합문헌진행토론。　결과　42례뇨로상피다기관암동기발생자17례，상계발생자25례，후자순뇨류방향발생자20례，역뇨류방향발생자5례。상계발생다기관암병례，불동기관리환암간기3개월～19년，<2년자18례，2～3년자3례，>3년자부4례。절대다수뇨로상피다기관암병례종류병리분급구유일치성。　결론　종류세포충식가능시뇨로상피다기관암발생적중요원인。
Objective　To study the occurring of multiple urinary organ involved urothelial carcinoma.　Methods　42 cases of multiple urinary organ involved urothelial carcinoma out of 527 cases of urothelial carcinoma were analyzed, with review of the literature.　Results　In this series the incidence of multiple urinary organ involved urothelial carcinoma was 7.96%, synchronous tumors occurred in 17 cases, metachronous tumors in 25 cases (down urine stream in 20 cases up urine stream in 5 cases).In 18 cases the metachronous tumors occurred within 2 years while only 4 cases over 3 years. In most cases,synchronous or metachronous histological grade was consistent.　Conclusions　Tumor cell implantation is possibly the most important mechanism in the occurring of multiple urinary organ involved urothelial carcinoma.