CAJ | 학술논문

[目的]探讨急性感染性腹泻患儿血清C反应蛋白(CRP)的变化及临床意义.[方法]对132例急性感染性腹泻患儿按病原体不同分为病毒性肠炎组82例和细菌性肠炎组50例;按病情程度不同分为重型腹泻组73例和轻型腹泻组59例.应用免疫比浊法测定血清CRP及血生化,同时测定53例健康对照组CRP.[结果]82例病毒性肠炎组及50例细菌性肠炎组CRP均明显高于对照组(P＜0.01),病毒性肠炎组与细菌性肠炎组比较CRP差异无显著性(P＞0.05),73例重型腹泻组与59例轻型腹泻组比较CRP差异有显著性(P＜0.01).[结论]急性感染性腹泻患儿CRP不能作为鉴别病毒或细菌感染的指标,但可作为评价病情严重与否的有用指标.
[목적]탐토급성감염성복사환인혈청C반응단백(CRP)적변화급림상의의.[방법]대132례급성감염성복사환인안병원체불동분위병독성장염조82례화세균성장염조50례;안병정정도불동분위중형복사조73례화경형복사조59례.응용면역비탁법측정혈청CRP급혈생화,동시측정53례건강대조조CRP.[결과]82례병독성장염조급50례세균성장염조CRP균명현고우대조조(P＜0.01),병독성장염조여세균성장염조비교CRP차이무현저성(P＞0.05),73례중형복사조여59례경형복사조비교CRP차이유현저성(P＜0.01).[결론]급성감염성복사환인CRP불능작위감별병독혹세균감염적지표,단가작위평개병정엄중여부적유용지표.
[Objective] To explore the change of serum C-reaction protein (CRP) level in the acute infectious diarrhea and evaluation its clinical significance. [Methods]A total of 132 cases of acute infectious diarrhea in children were divided into viral enteritis group(n=82) and bacterial enteritis group (n=50) by different pathogens. According to the degree of the disease state, all patients were divided into severe diarrhea group (n=73) and light diarrhea group (n=59). The serum CRP and blood biochemistry were measured by immunoturbidimetry method. Fifty three healthy children were selected as controls. [Results]The serum CRP level in the viral enteritis group and bacterial enteritis group was obviously higher than that in the control group(P<0.01). There was no significant difference between viral enteritis group and bacterial enteritis group (P>0.05). There was significant difference between severe diarrhea group and light diarrhea group (P<0.01). [Conclusion] The serum CRP level in the acute infectious diarrhea can not be the indicator for distinguishing viral and bacterial infections, but it can evaluate the disease severity.