中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2009年
11期
1111-1113
,共3页
柳洋%鲁恩洁%王玉林%狄飚%李铁钢%周勇%杨丽莉%许晓茵%傅传喜%王鸣
柳洋%魯恩潔%王玉林%狄飚%李鐵鋼%週勇%楊麗莉%許曉茵%傅傳喜%王鳴
류양%로은길%왕옥림%적표%리철강%주용%양려리%허효인%부전희%왕명
禽流感%H5N1%H9N2%H7N7%感染率
禽流感%H5N1%H9N2%H7N7%感染率
금류감%H5N1%H9N2%H7N7%감염솔
Avian influenza%H5N1%H9N2%H7N7%Infection rate
目的 应用血清流行病学调查广州市禽类从业人群感染禽流感病毒H5N1、H9N2、H7N7的状况,分析其感染特征.方法 采集广州市与禽类接触相关的职业人群血清,包括农贸市场活禽零售与非禽类零售人群、企业化家禽养殖与农村家禽散养人群、活禽批发市场人群、野生鸟驯养人群、生猪屠宰人群以及一般人群,用血凝抑制试验、中和抗体试验检测H5、H9、H7 IgG抗体;使用logistic回归分析、χ2检验分析感染率分布.结果 2881名调查对象中检测出4例H5抗体阳性(0.14%);146例H9抗体阳性(5.07%),其中以活禽零售人群H9感染率最高(14.96%),企业化家禽养殖人群为8.90%,活禽批发人群为6.69%,野生鸟驯养人群为3.75%,生猪养殖人群为2.40%,非禽类零售人群为2.21%,农村家禽散养人群为1.77%,一般人群为2.30%.而1926名禽类从业人群中H7抗体均为阴性.结论 人群中H5感染率较低,而H9感染率较高,未检测到H7感染;活禽零售、家禽批发、企业化家禽养殖等职业具有较高感染禽流感病毒的风险,其中以活禽零售感染风险最高,且接触家禽时间越长感染风险越高.
目的 應用血清流行病學調查廣州市禽類從業人群感染禽流感病毒H5N1、H9N2、H7N7的狀況,分析其感染特徵.方法 採集廣州市與禽類接觸相關的職業人群血清,包括農貿市場活禽零售與非禽類零售人群、企業化傢禽養殖與農村傢禽散養人群、活禽批髮市場人群、野生鳥馴養人群、生豬屠宰人群以及一般人群,用血凝抑製試驗、中和抗體試驗檢測H5、H9、H7 IgG抗體;使用logistic迴歸分析、χ2檢驗分析感染率分佈.結果 2881名調查對象中檢測齣4例H5抗體暘性(0.14%);146例H9抗體暘性(5.07%),其中以活禽零售人群H9感染率最高(14.96%),企業化傢禽養殖人群為8.90%,活禽批髮人群為6.69%,野生鳥馴養人群為3.75%,生豬養殖人群為2.40%,非禽類零售人群為2.21%,農村傢禽散養人群為1.77%,一般人群為2.30%.而1926名禽類從業人群中H7抗體均為陰性.結論 人群中H5感染率較低,而H9感染率較高,未檢測到H7感染;活禽零售、傢禽批髮、企業化傢禽養殖等職業具有較高感染禽流感病毒的風險,其中以活禽零售感染風險最高,且接觸傢禽時間越長感染風險越高.
목적 응용혈청류행병학조사엄주시금류종업인군감염금류감병독H5N1、H9N2、H7N7적상황,분석기감염특정.방법 채집엄주시여금류접촉상관적직업인군혈청,포괄농무시장활금령수여비금류령수인군、기업화가금양식여농촌가금산양인군、활금비발시장인군、야생조순양인군、생저도재인군이급일반인군,용혈응억제시험、중화항체시험검측H5、H9、H7 IgG항체;사용logistic회귀분석、χ2검험분석감염솔분포.결과 2881명조사대상중검측출4례H5항체양성(0.14%);146례H9항체양성(5.07%),기중이활금령수인군H9감염솔최고(14.96%),기업화가금양식인군위8.90%,활금비발인군위6.69%,야생조순양인군위3.75%,생저양식인군위2.40%,비금류령수인군위2.21%,농촌가금산양인군위1.77%,일반인군위2.30%.이1926명금류종업인군중H7항체균위음성.결론 인군중H5감염솔교저,이H9감염솔교고,미검측도H7감염;활금령수、가금비발、기업화가금양식등직업구유교고감염금류감병독적풍험,기중이활금령수감염풍험최고,차접촉가금시간월장감염풍험월고.
Objective To conduct serological investigation on H5N1/H9N2/H7N7 infection among people occupied in poultry fields. Methods Serum samples were collected from people working in live poultry and none-poultry retailing food markets, poultry wholesaling, large-scale poultry breading factories and in small-scale farms, wide birds breeding, swine slaughtering houses and from normal population. Antibodies of H5, H9 and H7 with hemagglutination inhibition and neutralization tests were tested and analyzed. Logistic regression and χ2 test were used. Results Among 2881 samples, 4 were positive to H5-Ab(0.14%), 146 were positive to H9-Ab (5.07%) and the prevalence of H9 among people from live poultry retailing (14.96%) was the highest. Prevalence rates of H9 were as follows: 8.90% in people working in the large-scale poultry breading factories, 6.69% in the live poultry wholesaling business, 3.75% in the wide birds breeding, 2.40% in the swine slaughtering, 2.21% in the non-poultry retailing, 1.77% in the rural poultry farmers and 2.30% in normal population. None was positive to H7-Ab among 1926 poultry workers. Conclusion The H5 prevalence among people was much lower than expected, but the H9 prevalence was higher. None of the populations tested was found positive to H7-Ab. There was a higher risk of AIV infection in live poultry retailing, wholesaling and large-scale breading businesses, with the risk of live poultry retailing the highest. The longer the service length was, the higher the risk existed.
