CAJ | 학술논문

目的探讨正常瞳孔下非球面及球面晶状体眼高阶像差的差别,分析计算非球面与球面晶状体消除球面像差的差值,以客观评价非球面人工晶状体的临床效果.方法回顾性临床对照研究.选取2010年1～4月在深圳市眼科医院行白内障超声乳化联合人工晶状体植入术的患者50例(66只眼).病人进行随机分组,分别植入非球面人工晶状体(KS-AIN)和球面人工晶状体(KS-X).术后1月正常瞳孔下(3～5mm),由itrace波前像差仪测量高阶像差及i-trace3.1软件模拟瞳孔直径3mm及5mm的调制传递函数值MTF.运用两样本t检验进行比较分析.结果正常瞳孔下非球面组球面像差小于球面组,其差异具有统计学意义(P<0.05);非球面晶状体与球面晶状体相比较可消除球面像差(0.069 ±0.026)μm(D-Value);非球面组高阶像差均方根小于球面组,但差异无统计学意义(P>0.05);彗差、三叶草比较亦无统计学意义(P>0.05);3mm瞳孔下两组晶状体MTF值的比较仅在空间频率5周/度差异有统计学意义(P<0.05).5mm瞳孔下非球面晶状体眼在各空间频率的MTF值均好于球面晶状体眼,比较有统计学意义(P<0.05).结论正常瞳孔下非球面人工晶状体眼与球面人工晶状体相比,可以有效减少球面像差,提高部分空间频率的对比敏感度,使患者拥有更好地视觉质量,但其不能体现可以减少术眼高阶像差的优势.
목적 탐토정상동공하비구면급구면정상체안고계상차적차별,분석계산비구면여구면정상체소제구면상차적차치,이객관평개비구면인공정상체적림상효과.방법 회고성림상대조연구.선취2010년1～4월재심수시안과의원행백내장초성유화연합인공정상체식입술적환자50례(66지안).병인진행수궤분조,분별식입비구면인공정상체(KS-AIN)화구면인공정상체(KS-X).술후1월정상동공하(3～5mm),유itrace파전상차의측량고계상차급i-trace3.1연건모의동공직경3mm급5mm적조제전체함수치MTF.운용량양본t검험진행비교분석.결과 정상동공하비구면조구면상차소우구면조,기차이구유통계학의의(P<0.05);비구면정상체여구면정상체상비교가소제구면상차(0.069 ±0.026)μm(D-Value);비구면조고계상차균방근소우구면조,단차이무통계학의의(P>0.05);혜차、삼협초비교역무통계학의의(P>0.05);3mm동공하량조정상체MTF치적비교부재공간빈솔5주/도차이유통계학의의(P<0.05).5mm동공하비구면정상체안재각공간빈솔적MTF치균호우구면정상체안,비교유통계학의의(P<0.05).결론 정상동공하비구면인공정상체안여구면인공정상체상비,가이유효감소구면상차,제고부분공간빈솔적대비민감도,사환자옹유경호지시각질량,단기불능체현가이감소술안고계상차적우세.
Objective To compare the high order aberrations between implantations of aspherical and spherical intraocular lens with normal pupil diameter, calculate and analyze the differences in spherical aberration between the eyes implanted with aspherical and spherical intraocular lens in order to assess the visual quality and investigate the clinical results. Methods Fifty patients(66 eyes)with cataract underwent surgery from Jan 2010 to Apr 2010, and were divided into 2 groups randomly. Group 1: unifocal and aspherical intraocular lens(negative aberration KS-AIN), Group2: unifocal and spherical intraocular lens(KS-X). Sixty-six eyes were included in this study. The aberrations at normal pupil diameter(interval 3mm-5mm)were measured with the i-Trace wavefront aberrometer. Modulation transfer functions were collected at 3mm and 5mm pupil size. Independent-Samples t Test was used to analyze the data. Results No post-operative complication occurred in each group. The average uncorrected visual acuity(UCVA)was ≥ 0.5, and the average best corrected visual acuity(BCVA)was ≥ 0.6. With normal pupil diameter(mean 3.73± 0.49mm), aspheric IOL group showed less spherical aberration than spherical IOL group with statistical significance(P =0.0040.05, t =-3.216), the difference value(D-value)of spherical aberration was 0.069± 0.026?m. Also aspheric IOL group showed less aberration than spherical IOL group in total higher-order root-mean-square(total HOA RMS)values, but with no statistical difference(P >0.05). There were no significant differences in coma and trefoil values between each group(P >0.05). With 3mm pupil diameter, aspheric IOL group provided a statistically better contrast sensitivity only in 5 cycle/degree while a statistically better contrast sensitivity in all spatial frequencies with 5mm pupil diameter. Conclusions The aspheric lens provides the patients better quality of vision at normal pupil size compared to spherical lens because of the decreased spherical aberration and a better contrast sensitivity in part frequencies. However, aspheric lens cannot express its superiority in decreasing total HOA RMS with normal pupil diameter.