CAJ | 학술논문

目的:观察鱼油脂肪乳对胃肠道恶性肿瘤病人术后营养状况和体液免疫的影响. 方法: 将30例胃肠道恶性肿瘤病人随机分为研究组和对照组,每组15例.术后两组病人使用等氮、等热量的PN支持,研究组添加鱼油脂肪乳.于术前、术后第1天和第6天分别检测血肝肾功能、血脂、Hb、ALB、TF、淋巴细胞计数(TLC)、B淋巴细胞亚群(B1、B2)、免疫球蛋白(IgG、IgM、IgA)和补体(C3、C4)水平. 结果: 两组病人术后第6天肝肾功能、血脂水平与术前相比均无显著性差异.研究组病人术后第6天TLC、IgG、IgM、C3显著高于对照组(P<0.05).两组病人Hb、ALB、TF和B淋巴细胞亚群无显著性差异. 结论: 胃肠道恶性肿瘤病人术后使用鱼油脂肪乳安全可耐受,能提高体液免疫功能,但在短期内病人的营养状况未见改善.
목적:관찰어유지방유대위장도악성종류병인술후영양상황화체액면역적영향. 방법: 장30례위장도악성종류병인수궤분위연구조화대조조,매조15례.술후량조병인사용등담、등열량적PN지지,연구조첨가어유지방유.우술전、술후제1천화제6천분별검측혈간신공능、혈지、Hb、ALB、TF、림파세포계수(TLC)、B림파세포아군(B1、B2)、면역구단백(IgG、IgM、IgA)화보체(C3、C4)수평. 결과: 량조병인술후제6천간신공능、혈지수평여술전상비균무현저성차이.연구조병인술후제6천TLC、IgG、IgM、C3현저고우대조조(P<0.05).량조병인Hb、ALB、TF화B림파세포아군무현저성차이. 결론: 위장도악성종류병인술후사용어유지방유안전가내수,능제고체액면역공능,단재단기내병인적영양상황미견개선.
Objective: To investigate the effects of ω-3 fish oil fat emulsion on nutritional status and humoral immunity in postoperative patients suffering from gastrointestinal malignancy. Methods: Thirty patients of gastrointestinal malignancy were randomly divided into study group (n = 15) and control group (n = 15). All the patients were assigned to receive total parenteral nutrition with the equal nitrogen and calory,and those in study group received fish oil fat emulsion additionally. Liver and renal function, blood lipid, haemoglobin, albumin, transferrin, total lymphocyte count (TLC) , B lymphocyte subsets (B1, B2), immunoglobin(IgG, IgM, IgA) and complement(C3, C4) were determined preoperatively and 1, 6d postoperatively. Results: There were no significant differences in liver and renal function and blood lipid on postoperative day 6 versus preoperation in all the two groups. TLC, IgG, IgM, C3 on postoperative day 6 were siginificantly higher in the study group(P < 0. 05). Haemoglobin, albumin, transferrin and B lymphocyte subsets were not significantly different between the two groups. Conclusion: Fish oil fat emulsion treatment was safe and tolerated, and could improve the humoral immunity in patients.