CAJ | 학술논문

目的了解上海市闵行区江川地区慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患病率及主要相关危险因素,为有效防治COPD提供依据.方法采用整群随机抽样方法,对该地区40岁以上人群进行问卷调查及肺功能检测,并以肺功能检测结果作为COPD的诊断依据.结果共有1 330例有效纳入本调查,平均年龄(62.44±11.3)岁,COPD总患病率为9.92%,男性患病率为14.66%,女性为6.77%,男性明显高于女性(χ2=22.254,P<0.000 1).所有COPD病例中,Ⅲ级患者为70例(占53.03%).单因素Logistic回归分析显示,性别、年龄、室内通风、家里灰尘、厨房排气装置、厨房居室分开、猛火炒菜、室外空气污染、职业接触粉尘、被动吸烟、主动吸烟、儿时反复发生支气管-肺部感染与COPD患病有统计学关系,而多因素Logistic回归分析显示年龄、主动吸烟、被动吸烟、室内通风、室外空气污染、职业接触粉尘、儿时反复发生支气管-肺部感染与COPD患病有关.结论上海市闵行区江川地区COPD患病率较高,COPD的发生与吸烟、室内外空气污染、职业接触粉尘及儿童时期患呼吸道疾病等因素有关.
목적 료해상해시민행구강천지구만성조새성폐질병(chronic obstructive pulmonary disease,COPD)환병솔급주요상관위험인소,위유효방치COPD제공의거.방법 채용정군수궤추양방법,대해지구40세이상인군진행문권조사급폐공능검측,병이폐공능검측결과작위COPD적진단의거.결과 공유1 330례유효납입본조사,평균년령(62.44±11.3)세,COPD총환병솔위9.92%,남성환병솔위14.66%,녀성위6.77%,남성명현고우녀성(χ2=22.254,P<0.000 1).소유COPD병례중,Ⅲ급환자위70례(점53.03%).단인소Logistic회귀분석현시,성별、년령、실내통풍、가리회진、주방배기장치、주방거실분개、맹화초채、실외공기오염、직업접촉분진、피동흡연、주동흡연、인시반복발생지기관-폐부감염여COPD환병유통계학관계,이다인소Logistic회귀분석현시년령、주동흡연、피동흡연、실내통풍、실외공기오염、직업접촉분진、인시반복발생지기관-폐부감염여COPD환병유관.결론 상해시민행구강천지구COPD환병솔교고,COPD적발생여흡연、실내외공기오염、직업접촉분진급인동시기환호흡도질병등인소유관.
Objective To investigate the prevalence of chronic obstructive pulmonary disease (COPD) and its major risk factors in Jiangchuan street, Minhang district of Shanghai, so as to provide scientific basis for preventing and controlling the COPD effectively. Methods Using the entire group random sampling method, we select residents of 40 years of age or older living in Jiangchuan street of Minhang district,to carry on the questionnaire survey and the lung function examination, with the results of lung function examination as the diagnoses basis for COPD. Results A total of 1 330 subjects were enrolled in this study,the mean age of these subjects was (62. 4 ±11. 3) years. The overall prevalence of COPD was 9. 92%, of which, the male prevalence was 14. 66%, the female prevalence was 6. 77%, the male prevalence was significantly higher than the female prevalence (χ2 = 22. 254, P <0. 000 1). Of the subjects with COPD, 70 subjects had COPD grade Ⅲ(53.03%). Single-factor non-conditional Logistic regression analysis showed that the following factors were statistically associated with the occurrence of COPD:gender,age,indoor ventilation status, there was dirt in the house, whether there was a releaser in the kitchen or not, whether the kitchen was separated from the living room or not, cooking with raging fire,outdoor air pollution,occupational exposure to dust,passive smoking,active smoking,and coughing in childhood. Multi-factor non-conditional Logistic regression analysis showed that the following factors were associated with the occurrence of COPD: age,active smoking, passive smoking, indoor ventilation status,outdoor air pollution, occupational exposure to dust, and coughing in childhood. Conclusions The prevalence of COPD in the residents of 40 years of age or older living in this Jiangchuan area, Minhang district of Shanghai,is quite high and related with smoking,air pollution,occupational exposure to dust,and coughing in childhood.