CAJ | 학술논문

患者男,12岁,眉、颊部红斑、毛囊性丘疹7年.以眉部红斑、毛囊性丘疹起病,渐蔓延至颊部、前额,后逐渐出现眉毛脱落,无瘙痒等不适.体检:眉部、前额、颊部暗红色斑片,边界尚清,其上有针头至米粒大小毛囊性丘疹,表面光滑,质稍硬,眉毛大部分脱落.皮损组织病理检查:毛囊口扩大,毛囊角栓,真皮浅层胶原纤维增粗、硬化,血管、毛囊周围少量淋巴组织细胞浸润.根据临床表现及皮肤组织病理,诊断为眉部瘢痕性红斑.治疗:口服维生素A 2.5万U每日1次,维生素E 100 mg每日1次,外用维生素E乳膏每日2次,0.025％维A酸软膏每晚1次.治疗2周后皮损改善.
환자남,12세,미、협부홍반、모낭성구진7년.이미부홍반、모낭성구진기병,점만연지협부、전액,후축점출현미모탈락,무소양등불괄.체검:미부、전액、협부암홍색반편,변계상청,기상유침두지미립대소모낭성구진,표면광활,질초경,미모대부분탈락.피손조직병리검사:모낭구확대,모낭각전,진피천층효원섬유증조、경화,혈관、모낭주위소량림파조직세포침윤.근거림상표현급피부조직병리,진단위미부반흔성홍반.치료:구복유생소A 2.5만U매일1차,유생소E 100 mg매일1차,외용유생소E유고매일2차,0.025％유A산연고매만1차.치료2주후피손개선.
A case of ulerythema ophryogenes (UO) is reported.A 12-year-old boy presented with erythema and follicular papules on the eyebrows and cheeks for 7 years.The lesions started as follicular papules surrounded by erythema,then spread symmetrically to the cheeks and forehead followed by the loss of eyebrows.There was no complaint of pruritus.Physical examination showed pinhead- to grain-sized,smooth,slightly indurated follicular hyperkeratotic papules surrounded by erythematous halo on the eyebrows,forehead and cheeks.Both eyebrows were nearly completely lost.Histological analysis of lesions from eyebrows revealed dilated follicular infundibulum with orthokeratotic plugs,sparse perivascular and perifollicular lymphohistiocytic infiltrate,widened and sclerotic collagen fibers in the dermis.According to the clinical manifestations and histopathological findings,the patient was diagnosed with ulerythema ophryogenes,and given oral vitamin A 2.5 million unit once a day,vitamin E 100 mg once a day,topical vitamine E cream twice a day,0.025％tretinoin ointment once at night.Two weeks later,the lesions improved.