上海交通大学学报（医学版）
上海交通大學學報（醫學版）
상해교통대학학보（의학판）
JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY(MEDICAL SCIENCE)
2009年
7期
886-889
,共4页
角膜新生血管%血管内皮生长因子%治疗
角膜新生血管%血管內皮生長因子%治療
각막신생혈관%혈관내피생장인자%치료
corneal neovascularization%vascular endothelial growth factor%treatment
角膜新生血管常继发于各类眼表疾病,引起角膜瘢痕和角膜移植术后排异反应,并可严重影响视力.近年研究发现,血管内皮生长因子(VEGF)在角膜新生血管化过程中起重要作用,而大量新型抗VEGF技术的问世为治疗角膜新生血管带来了希望.文章阐述了各种抑制VEGF的方法在治疗角膜新生血管方面的研究进展.
角膜新生血管常繼髮于各類眼錶疾病,引起角膜瘢痕和角膜移植術後排異反應,併可嚴重影響視力.近年研究髮現,血管內皮生長因子(VEGF)在角膜新生血管化過程中起重要作用,而大量新型抗VEGF技術的問世為治療角膜新生血管帶來瞭希望.文章闡述瞭各種抑製VEGF的方法在治療角膜新生血管方麵的研究進展.
각막신생혈관상계발우각류안표질병,인기각막반흔화각막이식술후배이반응,병가엄중영향시력.근년연구발현,혈관내피생장인자(VEGF)재각막신생혈관화과정중기중요작용,이대량신형항VEGF기술적문세위치료각막신생혈관대래료희망.문장천술료각충억제VEGF적방법재치료각막신생혈관방면적연구진전.
Corneal neovascularization is a significant and sight-threatening complication of many ocular surface disorders, and may cause corneal sear and rejection reaction after corneal grafting. Recent studies have revealed that vascular endothelial growth factor (VEGF) plays an important role in corneal neovascularization, and inhibition of VEGF has become a main strategy for treatment of corneal neovascularization. This article reviews the research progress in inhibition of corneal neovascularization by anti-VEGF therapy.
