CAJ | 학술논문

目的考察长白山产紫草的化学成分.方法石油醚加热回流提取,硅胶柱层析和制备硅胶薄层分离,重结晶得到单体化合物,利用理化性质及波谱学方法鉴定结构.结果分离鉴定了5个化合物,分别是去氧紫草素、β,β-二甲基丙烯酰紫草素、乙酰紫草素、2,3-二甲基戊烯酰紫草素和紫草素.结论去氧紫草素、β,β-二甲基丙烯酰紫草素、乙酰紫草素、2,3-二甲基戊烯酰紫草素和紫草素均为在长白山产紫草植物中首次发现.所得化学成分均为长白山产紫草与道地紫草所共有.
목적 고찰장백산산자초적화학성분.방법 석유미가열회류제취,규효주층석화제비규효박층분리,중결정득도단체화합물,이용이화성질급파보학방법감정결구.결과 분리감정료5개화합물,분별시거양자초소、β,β-이갑기병희선자초소、을선자초소、2,3-이갑기무희선자초소화자초소.결론 거양자초소、β,β-이갑기병희선자초소、을선자초소、2,3-이갑기무희선자초소화자초소균위재장백산산자초식물중수차발현.소득화학성분균위장백산산자초여도지자초소공유.
Objective To investigate the chemical constituents of Zicao (Radix Arnebiae) produced from Changbai Mountain.Methods Multi-chromatographic methods including reflux of petroleum ether, silica gel column chromatograph, preparative TLC and recrystallization were used to isolate the extracts from Zicao to get the monomeric compounds. The chemical structures of the extracts were identified based on the physicochemical characters and spectroscopic data.Results There were 5 chemical compounds extracted from Zicao, including deoxyshikonin, β,β'-dimethyl-acryl-shikonin, acetylshikonin, teracryl-shikonin and shikonin.Conclusion Deoxyshikonin, β,β'-dimethyl-acryl-shikonin, acetylshikonin, teracryl-shikonin and shikonin are found in Zicao produced from Changbai Mountain for the first time. The chemical constituents identified in Zicao produced from Changbai Mountain are the same as those in authentic Zicao.