CAJ | 학술논문

目的评估飞秒激光LASIK术后早期角膜中央和周边区敏感性的恢复情况.方法观察飞秒激光LASIK手术的患者40例(71只眼),分别在术前、术后1周、1月、3月使用Cohet-Bonnet角膜知觉计检查角膜中央、上方、下方、鼻侧和颞侧五个部位的敏感性,统计方法采用Kruskal Wallis H秩和检验和Mann-Whitney检验,以P＜0.05表示有统计学意义.结果飞秒激光LASIK手术后早期,在五个测量部位,术后1周、1月、3月角膜敏感性均低于术前,差异具有统计学意义(P＜0.05).术后1周、1月、3月各个时间段,角膜上方敏感性均高于其他部位,差异具有统计学意义(P＜0.05).术后3个月,中央区角膜敏感性小于其他部位,差异具有统计学意义(P＜0.05).中央角膜敏感性与角膜中央切削深度、中央角膜厚度、术前等效球镜度无相关性(r=0.005；-0.105；0.03,P=0.97；0.38; 0.80).结论飞秒激光LASIK术后早期角膜敏感性明显下降,角膜瓣蒂所在位置的敏感性较其他位置下降程度低,中央区角膜敏感性的恢复慢于其他位置,角膜中央敏感性与中央切削深度、角膜中央厚度、术前等效球镜度无相关.
목적 평고비초격광LASIK술후조기각막중앙화주변구민감성적회복정황.방법 관찰비초격광LASIK수술적환자40례(71지안),분별재술전、술후1주、1월、3월사용Cohet-Bonnet각막지각계검사각막중앙、상방、하방、비측화섭측오개부위적민감성,통계방법채용Kruskal Wallis H질화검험화Mann-Whitney검험,이P＜0.05표시유통계학의의.결과 비초격광LASIK수술후조기,재오개측량부위,술후1주、1월、3월각막민감성균저우술전,차이구유통계학의의(P＜0.05).술후1주、1월、3월각개시간단,각막상방민감성균고우기타부위,차이구유통계학의의(P＜0.05).술후3개월,중앙구각막민감성소우기타부위,차이구유통계학의의(P＜0.05).중앙각막민감성여각막중앙절삭심도、중앙각막후도、술전등효구경도무상관성(r=0.005；-0.105；0.03,P=0.97；0.38; 0.80).결론 비초격광LASIK술후조기각막민감성명현하강,각막판체소재위치적민감성교기타위치하강정도저,중앙구각막민감성적회복만우기타위치,각막중앙민감성여중앙절삭심도、각막중앙후도、술전등효구경도무상관.
Objective To evaluate the recovery of central corneal sensitivity and peripheral corneal sensitivity in the early period time after LASIK with femtosecond flaps.Methods In this study,40 cases which underwent LASIK with femtosecond flaps were included.Central,superior,inferior,nasal and temporal comeal sensitivity was measured using a Cochet-Bonnet esthesiometer (Luneau Ophthalmologie) before and 1 week,1 month and 3 months after LASIK with femtosecond flaps.The results were analyzed with Kruskal Wallis H test and Mann-Whitney test by SPSS13.0 software.Results Central,superior,inferior,nasal and temporal comeal sensitivity decreased significantly in the early period time after LASIK with femtosecond flap (P ＜0.05).At every time points of postoperative,superior corneal sensitivity and central,inferior,nasal and temporal corneal sensitivity had significant difference (P ＜0.05).Three months postoperative,central corneal sensitivity was significant lower than the superior,inferior,nasal,temporal.There were no correlations between central corneal sensitivity and central corneal ablation depth,central corneal depth,preoperative spherical equivalent (r =0.005;-0.105; 0,03,P =0.97; 0.38; 0.80). Conclusions Corneal sensitivity is significant decreased in the early period time after LASIK with femtosecond flaps.Comeal sensitivity at the location of the hinge of corneal flaps is decreased lower than other places and the recovery of central corneal sensitivity is slower than other places.There are no correlations between central corneal sensitivity and central corneal ablation depth,central corneal depth,preoperative spherical equivalent.