中华核医学杂志
中華覈醫學雜誌
중화핵의학잡지
CHINESE JOURNAL OF NUCLEAR MEDICINE
2010年
5期
329-332
,共4页
神经内分泌瘤%促肾上腺皮质激素%体层摄影术,发射型计算机%体层摄影术,X线计算机%脱氧葡萄糖
神經內分泌瘤%促腎上腺皮質激素%體層攝影術,髮射型計算機%體層攝影術,X線計算機%脫氧葡萄糖
신경내분비류%촉신상선피질격소%체층섭영술,발사형계산궤%체층섭영술,X선계산궤%탈양포도당
Neuroendocrine tumors%Adrenocorticotrophic hormone%Tomography,emission-computed%Tomography,X-ray computed%Deoxyglucose
目的 探讨18 F-脱氧葡萄糖(FDG)PET/CT定位诊断异位分泌促肾上腺皮质激素(ACTH)肿瘤的应用价值.方法 疑诊异位分泌ACTH患者共7例,其中男4例,女3例,年龄27～63岁.7例患者均根据临床症状、生化指标或岩下窦采血结果诊断为异位ACTH综合征,同时进行了头颅MR、胸腹部CT、腹部B超及18F-FDG PET/CT检查,以探查原发病灶,并对发现的病灶进行大小及最大标准摄取值(SUVmax)的测量.结果 7例患者中3例经18F-FDG PET/CT找到原发病灶,病灶大小分别为1.1 cm×1.0 cm、1.5 cm×1.1 cm、1.6 cm×1.5 cm,SUVmax值分别为9.4,6.4和12.0.随后对患者进行了肿瘤切除,病理检查结果分别为胸腺瘤、肺部类癌及纵隔类癌.原发灶检出率为3/7.结论 18F-FDG PET/CT在定位诊断异位分泌ACTH肿瘤中具有一定价值.
目的 探討18 F-脫氧葡萄糖(FDG)PET/CT定位診斷異位分泌促腎上腺皮質激素(ACTH)腫瘤的應用價值.方法 疑診異位分泌ACTH患者共7例,其中男4例,女3例,年齡27～63歲.7例患者均根據臨床癥狀、生化指標或巖下竇採血結果診斷為異位ACTH綜閤徵,同時進行瞭頭顱MR、胸腹部CT、腹部B超及18F-FDG PET/CT檢查,以探查原髮病竈,併對髮現的病竈進行大小及最大標準攝取值(SUVmax)的測量.結果 7例患者中3例經18F-FDG PET/CT找到原髮病竈,病竈大小分彆為1.1 cm×1.0 cm、1.5 cm×1.1 cm、1.6 cm×1.5 cm,SUVmax值分彆為9.4,6.4和12.0.隨後對患者進行瞭腫瘤切除,病理檢查結果分彆為胸腺瘤、肺部類癌及縱隔類癌.原髮竈檢齣率為3/7.結論 18F-FDG PET/CT在定位診斷異位分泌ACTH腫瘤中具有一定價值.
목적 탐토18 F-탈양포도당(FDG)PET/CT정위진단이위분비촉신상선피질격소(ACTH)종류적응용개치.방법 의진이위분비ACTH환자공7례,기중남4례,녀3례,년령27～63세.7례환자균근거림상증상、생화지표혹암하두채혈결과진단위이위ACTH종합정,동시진행료두로MR、흉복부CT、복부B초급18F-FDG PET/CT검사,이탐사원발병조,병대발현적병조진행대소급최대표준섭취치(SUVmax)적측량.결과 7례환자중3례경18F-FDG PET/CT조도원발병조,병조대소분별위1.1 cm×1.0 cm、1.5 cm×1.1 cm、1.6 cm×1.5 cm,SUVmax치분별위9.4,6.4화12.0.수후대환자진행료종류절제,병리검사결과분별위흉선류、폐부유암급종격유암.원발조검출솔위3/7.결론 18F-FDG PET/CT재정위진단이위분비ACTH종류중구유일정개치.
Objective To investigate the diagnostic value of 18F-fluorodeoxyglucose (FDG) PET/CT in the localization of ectopic adrenocorticotrophic hormone ( ACTH)-secreting tumors. Methods Seven patients with ectopic ACTH syndrome (confirmed by clinical symptom, biochemical data or bilateral simultaneous inferior petrosal sinus sampling) were included, 4 males and 3 females with age ranged 27-63 years old.All patients were examined with head MR, chest and abdomen CT, abdomen ultrasonography, and whole body 18F-FDG PET/CT. Location, size, and the maximum standardized uptake value (SUVmax) of the tumor were measured. Results 18 F-FDG PET/CT detected three ectopic ACTH-secreting tumors with the sizes 1. 1 cm×1.0 cm (SUVmax =9.4), 1.5 cm×1.1cm (SUVmax =6.4), and 1.6 cm ×1.5 cm (SUVmax =12.0). The pathological findings of the three tumors were thymoma, lung carcinoid, and mediastinal carcinoid respectively. Conclusion 18 F-FDG PET/CT may help the localization of ecto pic ACTH-secreting tumors .
