中华结核和呼吸杂志
中華結覈和呼吸雜誌
중화결핵화호흡잡지
Chinese Journal of Tuberculosis and Respiratory Diseases
2010年
10期
727-729
,共3页
王凌航%毛羽%赵红心%郜桂菊%肖江%梁宏远%杨涤%张黎颖%韩宁%李兴旺
王凌航%毛羽%趙紅心%郜桂菊%肖江%樑宏遠%楊滌%張黎穎%韓寧%李興旺
왕릉항%모우%조홍심%고계국%초강%량굉원%양조%장려영%한저%리흥왕
艾滋病%感染%支气管镜%病原分析
艾滋病%感染%支氣管鏡%病原分析
애자병%감염%지기관경%병원분석
HIV%Infection%Bronchoscopy%Pathogenic analysis
目的 评价支气管镜检查在艾滋病患者肺部感染病原诊断中的临床应用价值,探讨艾滋病合并肺部感染患者的病原谱及其分布.方法 收集2006年8月至2009年9月就诊于北京地坛医院的120例艾滋病合并肺部感染的患者,均行支气管镜检查及肺泡灌洗,收集BALF送检细菌培养及细胞病理检查;镜下可见明显组织异常者取支气管黏膜活检行病理学检查,并对患者的临床资料进行综合分析.结果 120例艾滋病合并肺部感染患者的BALF中,分枝杆菌抗酸染色阳性者30例,细菌培养阳性25例,肺孢子菌阳性12例,真菌培养阳性5例,巨细胞病毒阳性3例,阴性结果45例.26例行支气管黏膜活检,其中慢性炎性改变12例,鳞癌4例,腺癌2例,符合肉芽肿性炎性改变7例,淋巴瘤1例.结论 气管镜检查对艾滋病患者肺部感染病原学诊断具有明确的诊断价值.目前艾滋病合并肺部感染患者以结核病、细菌感染及肺孢子菌肺炎为主.
目的 評價支氣管鏡檢查在艾滋病患者肺部感染病原診斷中的臨床應用價值,探討艾滋病閤併肺部感染患者的病原譜及其分佈.方法 收集2006年8月至2009年9月就診于北京地罈醫院的120例艾滋病閤併肺部感染的患者,均行支氣管鏡檢查及肺泡灌洗,收集BALF送檢細菌培養及細胞病理檢查;鏡下可見明顯組織異常者取支氣管黏膜活檢行病理學檢查,併對患者的臨床資料進行綜閤分析.結果 120例艾滋病閤併肺部感染患者的BALF中,分枝桿菌抗痠染色暘性者30例,細菌培養暘性25例,肺孢子菌暘性12例,真菌培養暘性5例,巨細胞病毒暘性3例,陰性結果45例.26例行支氣管黏膜活檢,其中慢性炎性改變12例,鱗癌4例,腺癌2例,符閤肉芽腫性炎性改變7例,淋巴瘤1例.結論 氣管鏡檢查對艾滋病患者肺部感染病原學診斷具有明確的診斷價值.目前艾滋病閤併肺部感染患者以結覈病、細菌感染及肺孢子菌肺炎為主.
목적 평개지기관경검사재애자병환자폐부감염병원진단중적림상응용개치,탐토애자병합병폐부감염환자적병원보급기분포.방법 수집2006년8월지2009년9월취진우북경지단의원적120례애자병합병폐부감염적환자,균행지기관경검사급폐포관세,수집BALF송검세균배양급세포병리검사;경하가견명현조직이상자취지기관점막활검행병이학검사,병대환자적림상자료진행종합분석.결과 120례애자병합병폐부감염환자적BALF중,분지간균항산염색양성자30례,세균배양양성25례,폐포자균양성12례,진균배양양성5례,거세포병독양성3례,음성결과45례.26례행지기관점막활검,기중만성염성개변12례,린암4례,선암2례,부합육아종성염성개변7례,림파류1례.결론 기관경검사대애자병환자폐부감염병원학진단구유명학적진단개치.목전애자병합병폐부감염환자이결핵병、세균감염급폐포자균폐염위주.
Objective To evaluate the clinical value of bronchoscopy in the pathogenic diagnosis of AIDS patients with pulmonary infections and to illustrate the constituent ratio of different pulmonary pathogens. Methods From August 2006 to September 2009, we performed bronchoscopies to 120 AIDS patients who had pulmonary infections. We described the manifestations under the bronchoscope and each patient underwent bronchoalveolar lavage for further detection including bacterial culture and pathological test. We also took biopsies in patients who had obviously abnormal lesions under the bronchoscope. At the same time, we collected the clinical information for analyzing. Results Among 120 patients, we found 30 cases of mycobacteri infection, 25 cases of bacterial infection, 12 cases of PCP, 5 cases of fungal positive, 3 cases of CMV. Bronchial mucosa biopsies were taken in 26 patients, 12 cases of chronic inflammation, 7 cases of granulomatous inflammation, 4 cases of squamous cell carcinoma, 2 cases of adenocarcinoma and 1 case of lymphoma. Conclusion Bronchoscopy is a very useful tool and it's of great value for pathogenic detection in AIDS patients with pulmonary infections. At present, in China the main pulmonary infections in AIDS patients are TB, bacterial infection and PCP.
