CAJ | 학술논문

目的对先天性感染TORCH的新生儿进行临床分析.方法用ELASA法检测血清中TORCH(弓形体、风疹病毒、巨细胞病毒、单纯疱疹病毒)IgM.结果 2004年1月至2008年6月本院新生儿重症监护室共收治1352例,其中43例为TORCH感染,巨细胞病毒感染率为48.8%;风疹病毒感染占32.6%;单纯疱疹病毒感染占18.6%,未发现有弓形体感染者.其临床特点主要为听力异常、高胆红素血症和肝功能异常、神经系统损伤、心肌损伤、血小板减少、先天性心脏病等.结论新生儿TORCH感染可造成多器官损伤,危害性大,对可疑患儿进行筛查是必要的,预防应从母亲怀孕期开始
목적 대선천성감염TORCH적신생인진행림상분석.방법 용ELASA법검측혈청중TORCH(궁형체、풍진병독、거세포병독、단순포진병독)IgM.결과 2004년1월지2008년6월본원신생인중증감호실공수치1352례,기중43례위TORCH감염,거세포병독감염솔위48.8%;풍진병독감염점32.6%;단순포진병독감염점18.6%,미발현유궁형체감염자.기림상특점주요위은력이상、고담홍소혈증화간공능이상、신경계통손상、심기손상、혈소판감소、선천성심장병등.결론 신생인TORCH감염가조성다기관손상,위해성대,대가의환인진행사사시필요적,예방응종모친부잉기개시
Objective To search for the early clinical manifestations as evidences for prevention and treatment TORCH infections in newborns as early as possible. Methods ELASA was performed to screen specific anti-TORCH ( Toxoplasma gondlii, Cystomegalovirus, Rubella virus, Herpes simplex virus ) Ig-M antibodies.RESULTS Totally 1352 in-patients who were treated in Neonatal Intemaive Care Unit(NICU) of our hospital from January 2007 to June 2008 were retrospectively studied,43 of them had TORCH infections. Cytomegalovirus, rubella and herpes simples virus infections accounted for 48.8% ,32.6% and 18.6%, respectively. None of them had toxoplasma infection. The main clinical manifestations of them were hearing impairment, hyperbilirubinemias and liver dysfuntion,impairment of neurologic system, myocardial impairment, thrombocytopenia, and congenital heart disease. Conclusion TORCH infections can cause multiorgan lesions. Rubella vaccine inoculation, serological screening during pregnancy and early period of newborn, intervention and treatment in the early period are most important.