国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2012年
6期
417-420
,共4页
肺栓塞%肺栓塞再发%血浆纤维蛋白原
肺栓塞%肺栓塞再髮%血漿纖維蛋白原
폐전새%폐전새재발%혈장섬유단백원
Pulmonary embolism%Pulmonary embolism recurrence%Plasma fibrinogen
目的 观察并评价不同血浆纤维蛋白原水平与肺栓塞再发的关系.方法 回顾性分析77例初次肺栓塞患者治疗缓解后及24例肺栓塞再发患者的血浆纤维蛋白原水平,比较再发肺栓塞患者及未再发肺栓塞患者血浆纤维蛋白原水平是否存在显著差异,比较肺栓塞再发患者初次发病治疗缓解后及肺栓塞再发治疗前血浆纤维蛋白原水平之间的差异,同时分析肺栓塞再发患者栓塞灶分布与血浆纤维蛋白原升高之间的相关性.结果 再次发作肺栓塞患者血浆纤维蛋白原水平高于未再次发作肺栓塞患者(P＜0.05),肺栓塞再发组冶疗前血浆纤维蛋白原水平高于初次肺栓塞患者治疗缓解后血浆纤维蛋白原水平(P＜0.05),再次肺栓塞组血浆纤维蛋白原升高水平与患者的肺栓塞病灶分布无明显相关性(P＞0.05).结论 血浆纤维蛋白原升高与肺栓塞再发相关,纤维蛋白原升高是肺栓塞再发事件的重要危险因素,对肺栓塞再发有预测意义.
目的 觀察併評價不同血漿纖維蛋白原水平與肺栓塞再髮的關繫.方法 迴顧性分析77例初次肺栓塞患者治療緩解後及24例肺栓塞再髮患者的血漿纖維蛋白原水平,比較再髮肺栓塞患者及未再髮肺栓塞患者血漿纖維蛋白原水平是否存在顯著差異,比較肺栓塞再髮患者初次髮病治療緩解後及肺栓塞再髮治療前血漿纖維蛋白原水平之間的差異,同時分析肺栓塞再髮患者栓塞竈分佈與血漿纖維蛋白原升高之間的相關性.結果 再次髮作肺栓塞患者血漿纖維蛋白原水平高于未再次髮作肺栓塞患者(P＜0.05),肺栓塞再髮組冶療前血漿纖維蛋白原水平高于初次肺栓塞患者治療緩解後血漿纖維蛋白原水平(P＜0.05),再次肺栓塞組血漿纖維蛋白原升高水平與患者的肺栓塞病竈分佈無明顯相關性(P＞0.05).結論 血漿纖維蛋白原升高與肺栓塞再髮相關,纖維蛋白原升高是肺栓塞再髮事件的重要危險因素,對肺栓塞再髮有預測意義.
목적 관찰병평개불동혈장섬유단백원수평여폐전새재발적관계.방법 회고성분석77례초차폐전새환자치료완해후급24례폐전새재발환자적혈장섬유단백원수평,비교재발폐전새환자급미재발폐전새환자혈장섬유단백원수평시부존재현저차이,비교폐전새재발환자초차발병치료완해후급폐전새재발치료전혈장섬유단백원수평지간적차이,동시분석폐전새재발환자전새조분포여혈장섬유단백원승고지간적상관성.결과 재차발작폐전새환자혈장섬유단백원수평고우미재차발작폐전새환자(P＜0.05),폐전새재발조야료전혈장섬유단백원수평고우초차폐전새환자치료완해후혈장섬유단백원수평(P＜0.05),재차폐전새조혈장섬유단백원승고수평여환자적폐전새병조분포무명현상관성(P＞0.05).결론 혈장섬유단백원승고여폐전새재발상관,섬유단백원승고시폐전새재발사건적중요위험인소,대폐전새재발유예측의의.
Objective To observe and evaluate the relationship between different plasma fibrinogen levels and pulmonary embolism recurrence.Methods The plasma fibrinogen levels of 77 cases of remission in patients with initial pulmonary embolism and 24 cases of pulmonary embolism recurrence were retrospectively analyzed to observe whether there was a dominant difference plasma fibrinogen between the pulmonary embolism recurrence in patients and not recurrent pulmonary embolism in patients,to observe whether there was a dominant difference plasma fibrinogen level between pulmonary embolism recurrence of patients with initial onset of remission and pulmonary embolism recurrence with treatment,to analysis the relationship between pulmonary embolism recurrence and embolism stove distribution in patients.Results There were significant differences in plasma fibrinogen level between pulmonary embolism recurrence and not recurrence of pulmonary embolism in patients ( P ＜0.05).The plasma fibrinogen level of pulmonary embolism recurrence with pre-treatment was higher than the level of plasma fibrinogen after the initial pulmonary embolism in patients with remission ( P ＜0.05).There was no significant correlation between pulmonary embolism recurrence and embolism stove distribution ( P ＞0.05).Conclusions Elevated plasma fibrinogen is related to pulmonary embolism recurrence,fibrinogen is an important risk factor for pulmonary embolism events,can predict recurrence of pulmonary embolism.
