CAJ | 학술논문

利用静电纺丝法成功制备了尤特奇S100/β-环糊精（ES100／β-CD）纳米纤维．通过对纺丝条件的优化，从ES100佃．CD混合溶液中纺丝得到了表面光滑、分布均匀的圆柱状纳米纤维．研究结果发现，当ES100浓度较高时，β-CD在混合溶液中的浓度从2％逐渐增加至20％（w／w，以ES100为基准）均可得到无液珠的纳米纤维．在较低的ES100溶液浓度下，β-CD的加入有利于得到表面光滑的纳米纤维，纤维的平均直径随着卢-CD含量的增加而增大．红外光谱（FTIR）结果证实了所得纳米纤维中卢一CD的存在，ES100/β-CD的粉末X-射线衍射（XRD）光谱图中没有明显的衍射峰，说明β-CD分子在纳米纤维中分布均匀，没有形成结晶体和包合物．所制备的β-CD功能化的纳米纤维在药物输送系统和污水处理领域具有广泛的应用前景．
이용정전방사법성공제비료우특기S100/β-배호정（ES100／β-CD）납미섬유．통과대방사조건적우화，종ES100전．CD혼합용액중방사득도료표면광활、분포균균적원주상납미섬유．연구결과발현，당ES100농도교고시，β-CD재혼합용액중적농도종2％축점증가지20％（w／w，이ES100위기준）균가득도무액주적납미섬유．재교저적ES100용액농도하，β-CD적가입유리우득도표면광활적납미섬유，섬유적평균직경수착로-CD함량적증가이증대．홍외광보（FTIR）결과증실료소득납미섬유중로일CD적존재，ES100/β-CD적분말X-사선연사（XRD）광보도중몰유명현적연사봉，설명β-CD분자재납미섬유중분포균균，몰유형성결정체화포합물．소제비적β-CD공능화적납미섬유재약물수송계통화오수처리영역구유엄범적응용전경．
Eudragit S100/β-cyclodextrin （ES100/β-CD） nanofibers were successfully produced by electrospinning technique with the goal to develop functional nanowebs. Bead-free uniform electrospun ES100/β--CD nanofibers were obtained from homogeneous blend solutions of ESIOO/β-CD by optimizing the electrospinning conditions. The concentration of β-CD in the blend solution was varied from 2 % up to 20 % （w/w, with respect to the ES100 matrix）. It is found that the presence of β-CD in the ESIO0 solutions facilitates the electrospinning of bead-free nanofibers from the lower polymer concentrations, and the fiber diameter increased with the i.ncrease of β-CD content. Fourier transform infrared （FTIR） studies elucidate that β-CD molecules are presented in the nanowebs. The X-ray diffraction （XRD） spectra of ES100 /β-CD nanowebs did not show any significant diffraction peaks indicating that the β--CD molecules are homogeneously distributed within the ES100 matrix and does not form any phase separated crystalline aggregates. The β-CD functionalized nanowebs may have the potential to be used in waste treatment and drug delivery system.