CAJ | 학술논문

目的探讨术前免疫营养对小鼠肠切除术后早期肠功能障碍的影响.方法将80只小鼠随机分为4组,每组20只.术前分别给予瑞能肠内免疫营养支持3d、5d、7d及常规饮食准备.继即在小肠部分切除术24h后,行炭末灌胃,以炭末在小鼠小肠内的推进率为观察指标进行比较.结果肠内免疫营养3d、5d及7d各组炭末推进率与常规准备组比较,差异有统计学意义.肠内免疫营养3d、5d、7d三组间炭末推进率差异无统计学意义.结论术前使用肠内免疫营养剂能明显改善小鼠肠切除术后早期小肠蠕动,但改善程度与使用时间无明显联系.
목적 탐토술전면역영양대소서장절제술후조기장공능장애적영향.방법 장80지소서수궤분위4조,매조20지.술전분별급여서능장내면역영양지지3d、5d、7d급상규음식준비.계즉재소장부분절제술24h후,행탄말관위,이탄말재소서소장내적추진솔위관찰지표진행비교.결과 장내면역영양3d、5d급7d각조탄말추진솔여상규준비조비교,차이유통계학의의.장내면역영양3d、5d、7d삼조간탄말추진솔차이무통계학의의.결론 술전사용장내면역영양제능명현개선소서장절제술후조기소장연동,단개선정도여사용시간무명현련계.
Objective To explore the influence of preoperative enteral immune nutrition on the early stage intestinal malfunction after entereetomy in mice. Methods 80 mice were divided into 4 groups randomly, with 20 in each group, 3 group for treatment and 1 for control. Enteral immune nutrition was administered 3d ,5d ,7d in the treating group and routine preoperative diet was given in control group. All the mice had intragastric administration of earbo medicinalis after entereetomy, intra - intestinal propulsive movement were measured and compared. Results There was significant difference of intra - intestinal propulsive movement in all the treating group compared with that in control group. while among the treating groups, the difference was notsignificant. Conclusions The preoperative enteral immune nutrition improves the intestinal movements in the early stage of entereetomy in mice, yet the degree of improvement is not correlated to the time of administering.