中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2009年
18期
42-43
,共2页
胃肠外科%细菌感染%药敏%合理用药
胃腸外科%細菌感染%藥敏%閤理用藥
위장외과%세균감염%약민%합리용약
Stomach enterochirurgia%Bacterial infection%Drug susceptibility%Rational use of drug
目的 了解本院胃肠外科手术患者感染常见细菌及药敏结果 ,以指导临床合理用药.方法 对70例胃肠外科手术患者采集77株细菌进行鉴定及药敏分析.结果 其中G+细菌为17株,占22.08%.G-细菌为60株,占77.92%.第一位致病菌为大肠埃希菌,第二位为铜绿假单胞菌和克雷伯杆菌,第四位致病菌为肠球菌.同时感染两种以上细菌的病例有19例.第3,4代头孢菌素类和碳青霉烯类对大肠埃希菌,克雷伯杆菌和铜绿假单胞菌均有良好的疗效.2代头孢菌素疗效稍差.氨基糖甙类疗效欠佳,喹诺酮类药物中加替沙星疗效好于环丙沙星.结论 胃肠手术感染细菌主要来源于肠道细菌,因为耐药性各不相同,感染发生时最好根据细菌培养和药敏的结果 用药,经验及预防用药时最好选择广谱抗生素.
目的 瞭解本院胃腸外科手術患者感染常見細菌及藥敏結果 ,以指導臨床閤理用藥.方法 對70例胃腸外科手術患者採集77株細菌進行鑒定及藥敏分析.結果 其中G+細菌為17株,佔22.08%.G-細菌為60株,佔77.92%.第一位緻病菌為大腸埃希菌,第二位為銅綠假單胞菌和剋雷伯桿菌,第四位緻病菌為腸毬菌.同時感染兩種以上細菌的病例有19例.第3,4代頭孢菌素類和碳青黴烯類對大腸埃希菌,剋雷伯桿菌和銅綠假單胞菌均有良好的療效.2代頭孢菌素療效稍差.氨基糖甙類療效欠佳,喹諾酮類藥物中加替沙星療效好于環丙沙星.結論 胃腸手術感染細菌主要來源于腸道細菌,因為耐藥性各不相同,感染髮生時最好根據細菌培養和藥敏的結果 用藥,經驗及預防用藥時最好選擇廣譜抗生素.
목적 료해본원위장외과수술환자감염상견세균급약민결과 ,이지도림상합리용약.방법 대70례위장외과수술환자채집77주세균진행감정급약민분석.결과 기중G+세균위17주,점22.08%.G-세균위60주,점77.92%.제일위치병균위대장애희균,제이위위동록가단포균화극뢰백간균,제사위치병균위장구균.동시감염량충이상세균적병례유19례.제3,4대두포균소류화탄청매희류대대장애희균,극뢰백간균화동록가단포균균유량호적료효.2대두포균소료효초차.안기당대류료효흠가,규낙동류약물중가체사성료효호우배병사성.결론 위장수술감염세균주요래원우장도세균,인위내약성각불상동,감염발생시최호근거세균배양화약민적결과 용약,경험급예방용약시최호선택엄보항생소.
Objective To investigate the characteristics of common bacterial and drug-sensitive of stomach intestine surgery infection in our hospital. Methods 77 strains of bacteria collected from 70 patients with stomach intestine operation were identified and tested for the susceptibility to antibiotics.Results Bacteria positive rate included Gram-negative bacteria 60(77.92% ) and Gram-positive bacteria 17(22.08% ). The first pathogenic bacteria was Escherichia coli, the second was Klebsiella and pseudomonas aerumginosa , and the fourth was enterococcus. There were 19 cases who were co-infected two or above basteria. The third and fourth generations of Cephalosporins were commonly used in clinical treatment with the obvious anti-G-and-G+ bacteria. The second generation of Cephalosporins were not so effective and aminoglycosides were below the mark. Gatifloxacin had better effects than Ciprofloxacin in Quinolones. Conclusions The tendency to antimicrobial resistance of clinical isolates should be followed up continuously. Selection of antimicrobial should be based on result of bacteria culture.
